For researchers and procurement professionals in the pharmaceutical and biotechnology sectors, the careful selection of chemical reagents is fundamental to the success of their projects. Fmoc-D-3-Bromophenylalanine is a specialized amino acid derivative that plays a critical role in advanced peptide synthesis, drug development, and bioconjugation. Knowing where to source this compound and what to look for ensures the integrity and efficiency of your research. If you are looking to buy Fmoc-D-3-Bromophenylalanine, this guide will provide essential insights.

The primary application of Fmoc-D-3-Bromophenylalanine is as a protected building block in Solid-Phase Peptide Synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) group protects the alpha-amino terminus of the amino acid, allowing for selective coupling reactions during peptide chain elongation. Its removal under mild basic conditions is a hallmark of Fmoc chemistry, preserving the integrity of the peptide. The ‘D’ configuration indicates the specific stereoisomer, crucial for synthesizing peptides with defined biological activity. High purity is paramount for these applications to avoid unwanted side reactions or impurities in the final peptide product.

The ‘3-Bromo’ modification on the phenyl ring is what truly distinguishes this molecule. This bromine atom serves as a reactive site for a variety of subsequent chemical transformations. In medicinal chemistry, this allows for the introduction of diverse functionalities through cross-coupling reactions, enabling the fine-tuning of peptide properties for therapeutic applications. Whether you are developing novel peptide-based drugs, creating complex peptide libraries for screening, or performing intricate bioconjugations, the quality of your Fmoc-D-3-Bromophenylalanine directly impacts your outcomes.

When sourcing Fmoc-D-3-Bromophenylalanine, consider the following factors:

  • Purity: Look for specifications indicating high purity, typically 97% or higher, with clear analytical data (e.g., HPLC, NMR) provided by the manufacturer. For pharmaceutical intermediates, higher purities are often required.
  • Stereochemical Integrity: Ensure the product is indeed the D-isomer as required for your specific synthesis, with documented chiral purity.
  • Manufacturer Reputation: Partner with established manufacturers and suppliers known for their quality control and consistency. Companies with ISO certifications or strong reputations in the fine chemical or pharmaceutical intermediate space are good starting points.
  • Availability and Lead Times: For ongoing research or production, consistent availability and reasonable lead times are crucial. Understanding a supplier’s inventory and production capacity is important.
  • Pricing: While cost is always a consideration, prioritize quality and reliability over the lowest price. Obtaining a quote from a reputable supplier can help in budgeting.

We are a dedicated manufacturer and supplier of high-quality chemical intermediates, including Fmoc-D-3-Bromophenylalanine. Our commitment is to provide researchers and companies with the reliable reagents they need to drive innovation. By choosing us, you ensure access to a premium product manufactured under stringent quality controls, supported by knowledgeable customer service. When it’s time to purchase this critical component for your peptide synthesis or drug development projects, consider the advantages of partnering with a trusted provider. We aim to be your go-to source for specialized amino acid derivatives.