For procurement managers and R&D scientists in the pharmaceutical and biotechnology sectors, sourcing high-quality reagents is paramount. Among these, Fmoc-Sta-OH (CAS 158257-40-0) stands out as a critical building block, particularly for those engaged in complex peptide synthesis and drug development. Understanding the nuances of purchasing this compound can significantly impact project success and cost-efficiency. This guide aims to equip you with the essential knowledge to make informed decisions when you need to buy Fmoc-Sta-OH.

Understanding Fmoc-Sta-OH: The Foundation of Your Peptide Synthesis

Fmoc-Sta-OH, or N-Fmoc-L-Statine, is a non-proteinogenic amino acid derivative widely employed in solid-phase peptide synthesis (SPPS). Its structure incorporates the fluorenylmethoxycarbonyl (Fmoc) protecting group, which is labile under mild basic conditions, allowing for selective deprotection and sequential amino acid coupling. This characteristic is fundamental to building precise peptide sequences. For many applications, especially in developing therapeutic peptides for oncology or metabolic disorders, a high purity level, often ≥98%, is non-negotiable. The presence of trace impurities can lead to incomplete reactions, side products, and compromised final peptide efficacy. Therefore, when inquiring about Fmoc-Sta-OH price, always ensure the purity specification is clearly stated and meets your project's demands.

Key Considerations When Purchasing Fmoc-Sta-OH

As a procurement specialist, several factors should guide your supplier selection. Firstly, reliability of the manufacturer is crucial. Look for suppliers who not only offer competitive Fmoc-Sta-OH price but also demonstrate a robust quality control system. Certificates of Analysis (CoA) detailing purity (e.g., via HPLC) and optical rotation are essential documents. Secondly, consider the supply chain stability. Sourcing from a manufacturer based in China can offer cost advantages, but it's vital to partner with established companies that have a proven track record of consistent delivery and adherence to international quality standards.

When you search for an 'Fmoc-Sta-OH supplier,' pay attention to companies that specialize in pharmaceutical intermediates and chiral building blocks. These suppliers often possess the technical expertise and infrastructure to handle such specialized chemicals. Furthermore, inquire about packaging and storage recommendations. Typically, Fmoc-Sta-OH requires storage at low temperatures (e.g., -20°C) to maintain its integrity. A supplier that provides appropriate packaging and clear storage instructions ensures you receive a product that remains potent.

Navigating the Market: Pricing and Bulk Orders

The Fmoc-Sta-OH price can vary significantly based on purity, quantity, and the supplier. For research quantities, prices might be higher per gram, reflecting development costs. However, for larger-scale production or ongoing research needs, bulk purchasing from a direct manufacturer can lead to substantial cost savings. When requesting a quote for 'Fmoc-Sta-OH wholesale,' be prepared to specify your required quantity and purity. Many manufacturers, like NINGBO INNO PHARMCHEM CO.,LTD., offer custom synthesis services, which can be beneficial if specific modifications or higher quantities are needed.

To summarize, when you intend to buy Fmoc-Sta-OH for your critical peptide synthesis projects, prioritize purity, supplier reliability, and secure supply chains. By carefully evaluating these factors and obtaining detailed quotes, you can ensure you are partnering with the right pharmaceutical intermediate manufacturer, paving the way for successful drug discovery and development.