In the relentless pursuit of novel therapeutics, the availability of high-quality chemical intermediates is paramount. Furo[3,4-b]pyrazine-5,7-dione, identified by CAS number 4744-50-7, stands out as a critical building block in pharmaceutical research and development. Its unique heterocyclic structure, featuring fused furan and pyrazine rings, makes it an invaluable compound for organic synthesis and the creation of advanced pharmaceutical agents. If you are a procurement manager or a research scientist looking to buy this essential intermediate, understanding its properties and reliable sourcing channels is key.

Furo[3,4-b]pyrazine-5,7-dione, also known commonly as 2,3-pyrazinedicarboxylic anhydride, is a white crystalline powder with a high purity level, often exceeding 99%. This purity is non-negotiable for applications in medicinal chemistry, where even trace impurities can significantly impact reaction outcomes and the efficacy of the final drug product. Its molecular formula is C6H2N2O3, and its molecular weight is approximately 150.09 g/mol. The compound's stability and reactivity profile make it an attractive precursor for synthesizing a wide array of complex organic molecules, including potential anticancer and antimicrobial compounds. Researchers often leverage its ability to undergo various chemical transformations, such as oxidation, reduction, and substitution reactions, to introduce diverse functional groups and create novel derivatives with specific biological activities.

The synthesis of Furo[3,4-b]pyrazine-5,7-dione typically involves the intramolecular cyclization of pyrazine-2,3-dicarboxylic acid under dehydrating conditions. Common reagents used in this process include acetic anhydride or phosphorus oxychloride, often carried out under reflux. For procurement managers seeking to ensure a stable supply chain, identifying a reputable manufacturer is crucial. Companies specializing in fine chemicals and pharmaceutical intermediates, particularly those based in China, often provide competitive pricing and bulk quantities. When evaluating suppliers, look for manufacturers that can provide detailed Certificates of Analysis (CoA), confirming the purity and specifications of the product, which is vital for GMP compliance and research integrity.

For those involved in drug discovery, understanding the application landscape of Furo[3,4-b]pyrazine-5,7-dione is essential. Its derivatives have shown promising results in preclinical studies, including cytotoxic activity against various cancer cell lines and significant antibacterial properties against Gram-positive bacteria. This broad spectrum of potential applications underscores its importance as a pharmaceutical intermediate. As a chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and manufacturers with this high-quality intermediate, ensuring a reliable source for your critical research and development needs. We understand the importance of timely delivery and consistent quality, making us a trusted partner for your chemical sourcing requirements. If you are looking to purchase Furo[3,4-b]pyrazine-5,7-dione or require a custom synthesis quote, please reach out to our sales team.