The quest for effective treatments for fibrotic and autoimmune diseases necessitates advanced research compounds. Halofuginone (CAS 55837-20-2) has emerged as a significant molecule in this domain, primarily due to its potent antifibrotic and immunomodulatory capabilities. Understanding its impact and ensuring a reliable supply chain are key for researchers focused on these complex conditions.

As a derivative of febrifugine, Halofuginone functions as a competitive inhibitor of prolyl-tRNA synthetase. This inhibition directly impacts the synthesis of collagen type I, a critical factor in the development of fibrosis in various organs, including skin, lungs, and liver. For scientists studying conditions like scleroderma, idiopathic pulmonary fibrosis, or liver fibrosis, purchasing high-quality Halofuginone is instrumental in exploring potential therapeutic strategies. Its ability to attenuate osteoarthritis by inhibiting TGF-β activity further broadens its research applications.

In the realm of autoimmune diseases, Halofuginone's role in modulating immune cell differentiation is particularly noteworthy. Research indicates that it can suppress the development of Th17 cells, which are often implicated in the pathogenesis of autoimmune disorders. By selectively targeting these cells, Halofuginone offers a nuanced approach to immune system regulation. Scientists can buy Halofuginone to investigate its therapeutic potential in models of diseases such as rheumatoid arthritis, psoriasis, and multiple sclerosis.

NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer and supplier of pharmaceutical intermediates from China, understands the critical need for high-purity research chemicals. We offer Halofuginone to support your groundbreaking research. Our commitment ensures that you can purchase Halofuginone with the assurance of quality and consistency, facilitating your work in understanding and combating fibrotic and autoimmune conditions. Engage with us to secure your supply and advance your scientific discoveries.