Sourcing High-Purity (1-Boc-5,6-dichloro-1H-indol-2-yl)boronic Acid: A Buyer's Guide
For professionals in the pharmaceutical and fine chemical industries, sourcing high-quality building blocks is paramount. Among these, (1-(tert-Butoxycarbonyl)-5,6-dichloro-1H-indol-2-yl)boronic acid, often referred to as 1-Boc-5,6-dichloro-1H-indol-2-yl)boronic acid, stands out as a crucial intermediate. If you are looking to buy this compound, understanding its specifications and identifying a reliable manufacturer or supplier, particularly from China, is essential for efficient procurement and successful synthesis.
Understanding the Compound's Value
(1-(tert-Butoxycarbonyl)-5,6-dichloro-1H-indol-2-yl)boronic acid (CAS 1310384-28-1) is a highly functionalized indole derivative that plays a significant role in organic synthesis. Its unique chemical structure, featuring a protected indole core with a boronic acid moiety and dichloro substitutions, makes it an invaluable precursor for creating complex molecules. Its primary applications lie within the pharmaceutical sector, where it serves as a key intermediate in the development of novel therapeutic agents and active pharmaceutical ingredients (APIs). The 'Boc' (tert-butoxycarbonyl) group provides protection during sensitive reaction steps, while the boronic acid function is key for palladium-catalyzed cross-coupling reactions, such as Suzuki couplings, enabling the facile formation of carbon-carbon bonds.
Key Considerations for Procurement
When searching for a supplier of (1-(tert-Butoxycarbonyl)-5,6-dichloro-1H-indol-2-yl)boronic acid, several factors must be prioritized to ensure you receive a product that meets your exacting requirements. Firstly, purity is critical. Most reputable manufacturers will offer this compound with a purity of 97% or higher, as specified in technical data sheets. This high level of purity is vital to avoid side reactions and ensure the efficacy and safety of the final pharmaceutical product. Secondly, understand the CAS number (1310384-28-1) associated with the compound, as this is the universal identifier used across the chemical industry. Requesting a free sample can be a prudent step to verify quality and suitability for your specific application before committing to a larger purchase.
Finding a Reliable China Manufacturer
China has emerged as a global hub for chemical manufacturing, offering competitive prices and a wide range of specialized intermediates. For (1-(tert-Butoxycarbonyl)-5,6-dichloro-1H-indol-2-yl)boronic acid, partnering with an established China manufacturer can provide significant advantages in terms of cost-effectiveness and supply chain reliability. Look for suppliers who demonstrate a commitment to quality control, possess robust production capabilities, and have a track record of successful international trade. Engaging with manufacturers directly can often lead to better pricing and greater flexibility in terms of order quantities and packaging. When you purchase this intermediate, ensure the supplier can provide comprehensive technical documentation, including Certificates of Analysis (CoA), and is transparent about their manufacturing processes.
Concluding Thoughts on Purchasing
The decision to buy (1-(tert-Butoxycarbonyl)-5,6-dichloro-1H-indol-2-yl)boronic acid is a strategic one for any research and development project. By focusing on purity, understanding the CAS number, and selecting a trusted manufacturer or supplier from China, you can secure a high-quality chemical intermediate that will support your synthesis goals. We, as a leading chemical supplier, are dedicated to providing researchers and businesses with the essential materials they need to drive innovation forward. Contact us today to get a quote and sample.
Perspectives & Insights
Logic Thinker AI
“Look for suppliers who demonstrate a commitment to quality control, possess robust production capabilities, and have a track record of successful international trade.”
Molecule Spark 2025
“Engaging with manufacturers directly can often lead to better pricing and greater flexibility in terms of order quantities and packaging.”
Alpha Pioneer 01
“When you purchase this intermediate, ensure the supplier can provide comprehensive technical documentation, including Certificates of Analysis (CoA), and is transparent about their manufacturing processes.”