For procurement managers and R&D scientists in the chemical and pharmaceutical industries, securing a consistent and reliable supply of high-quality intermediates is paramount to project success. Among the vast array of chemical building blocks, 1H-indole-2,5-dicarboxylic acid (CAS 117140-77-9) has emerged as a compound of significant interest due to its versatile reactivity and diverse applications. As a leading manufacturer and supplier of fine chemicals, we understand the stringent requirements of our B2B clients and are dedicated to providing this crucial intermediate with the utmost purity and reliability.

1H-indole-2,5-dicarboxylic acid, presented as a white to light yellow crystalline powder, boasts a molecular formula of C₁₀H₇NO₄ and a molecular weight of 205.17 g/mol. Its defining feature is the presence of two carboxylic acid groups attached to the indole nucleus. This structural characteristic makes it an exceptionally useful synthon in organic synthesis. The indole ring itself is a prevalent motif in many biologically active molecules, while the dicarboxylic acid functionality allows for a wide range of derivatization reactions, including esterification, amidation, and participation in coordination chemistry.

The demand for 1H-indole-2,5-dicarboxylic acid is driven by its application in several high-value sectors. In the pharmaceutical industry, it serves as a key intermediate for the synthesis of novel drug candidates. Researchers are actively exploring its derivatives for their potential as antiviral agents, particularly as inhibitors of HIV-1 integrase, and for anticancer therapies, by targeting metabolic pathways in cancer cells. The purity of the intermediate is critical in these applications to ensure the efficacy and safety of the final drug product. Therefore, when considering purchasing this compound, it is essential to partner with a manufacturer that can guarantee a high assay, typically ≥98.0%.

Beyond pharmaceuticals, 1H-indole-2,5-dicarboxylic acid finds utility in the burgeoning field of material science. Its dicarboxylic nature makes it an excellent candidate for use as an organic linker in the construction of Metal-Organic Frameworks (MOFs). These advanced porous materials are gaining significant traction for their applications in gas storage, catalysis, and separation. The ability to reliably source this intermediate in bulk quantities is crucial for companies looking to scale up MOF production.

For procurement managers, selecting a supplier involves more than just comparing prices. It requires a thorough assessment of quality control measures, production capacity, and the ability to provide consistent shipments. As a manufacturer based in China, we leverage efficient synthetic processes and stringent quality assurance protocols to deliver 1H-indole-2,5-dicarboxylic acid that meets international standards. We understand that supply chain stability is vital, and we are committed to ensuring timely deliveries and responsive customer service.

When sourcing 1H-indole-2,5-dicarboxylic acid, inquire about its physical and chemical properties, such as melting point and solubility, to ensure it aligns with your specific process requirements. We recommend requesting technical data sheets and Certificates of Analysis with every order. For companies looking to purchase this essential intermediate, engaging directly with a manufacturer like us can offer significant advantages, including competitive pricing, technical support, and the assurance of product quality. Contact our sales team today to discuss your requirements and obtain a quote for 1H-indole-2,5-dicarboxylic acid.