For pharmaceutical companies and R&D laboratories, securing a consistent and high-quality supply of essential chemical intermediates is paramount. One such crucial compound is 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid, identified by CAS number 5270-74-6. This article aims to guide procurement managers and research scientists on how to effectively source this vital intermediate, emphasizing key considerations like purity, supplier reliability, and cost-effectiveness.

Understanding the Compound: Properties and Applications

2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid is a white to pale beige solid with a molecular formula of C14H10ClNO5S and a molecular weight of 339.75. Its primary role is as a pharmaceutical intermediate, often utilized in the synthesis of Active Pharmaceutical Ingredients (APIs) and as a reference standard in drug metabolism studies. Its specific chemical structure makes it invaluable for complex organic synthesis pathways. The demand for this compound is driven by the pharmaceutical industry's continuous need for novel drug development and the optimization of existing manufacturing processes. Procurement professionals must ensure the intermediate meets strict purity specifications, often exceeding 95% by HPLC, to guarantee the efficacy and safety of the final drug product.

Key Considerations for Sourcing

When looking to buy 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid, several factors should be prioritized:

  • Purity and Quality: Always request a Certificate of Analysis (CoA) that details the purity, physical characteristics, and analytical methods used. High purity is critical for successful synthesis and regulatory compliance.
  • Supplier Reliability: Partnering with established chemical suppliers who have strong relationships with reputable manufacturers is essential. This ensures consistent product quality and dependable delivery schedules. Many leading suppliers have established GMP (Good Manufacturing Practice) protocols for their production.
  • Supply Chain Stability: Inquire about the manufacturer's production capacity and their ability to meet your volume requirements, whether for R&D or large-scale commercial production. A stable supply chain is crucial to avoid production delays.
  • Regulatory Compliance: Ensure the supplier can provide necessary documentation, such as MSDS (Material Safety Data Sheet) and compliance with relevant chemical regulations in your region.

Finding the Right Supplier: The China Advantage

China has emerged as a global hub for chemical manufacturing, offering a wide array of intermediates at competitive prices. For those seeking to purchase 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid, working with a trusted Chinese manufacturer or distributor can provide significant advantages. Companies specializing in fine chemicals and pharmaceutical intermediates often have state-of-the-art facilities and adhere to international quality standards. When selecting a supplier, look for those who offer transparent pricing, responsive customer service, and a proven track record in the B2B chemical market.

Navigating Pricing and Bulk Orders

The price of 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid can vary based on purity, quantity, and supplier. For bulk orders, negotiation is often possible, leading to substantial cost savings. Many suppliers offer tiered pricing structures, making larger orders more economical. To obtain the best possible quote, it is advisable to contact multiple suppliers and compare their offerings, considering not just the price but also the overall value proposition, including quality assurance and logistical support.

In conclusion, sourcing 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzoic Acid requires a strategic approach. By focusing on purity, supplier reputation, and cost-effectiveness, pharmaceutical companies can secure a reliable supply of this critical intermediate. Leveraging the expertise of established chemical suppliers in China ensures access to high-quality materials, supporting the advancement of pharmaceutical research and manufacturing.