For procurement managers and R&D scientists in the chemical and pharmaceutical sectors, identifying reliable sources for critical intermediates like 2-Bromo-4-fluorobenzoic acid (CAS 1006-41-3) is paramount. This compound, with its unique chemical structure, serves as a vital building block in numerous synthesis pathways. Understanding its properties and where to buy it can significantly impact project timelines and product efficacy.

Understanding 2-Bromo-4-fluorobenzoic Acid (CAS 1006-41-3)

2-Bromo-4-fluorobenzoic acid is a halogenated aromatic carboxylic acid. Its molecular formula is C7H4BrFO2, and it typically presents as a white to off-white crystalline powder. With a molecular weight of 219.01 and a melting point generally between 172-176°C, its purity is often specified at 98.0% minimum for applications in fine chemical synthesis. Its strategic placement of bromine and fluorine atoms makes it highly reactive and useful in various organic transformations, especially in the synthesis of fluorinated compounds, which are known for enhanced biological activity and stability.

Key Applications and User Needs

The primary demand for 2-Bromo-4-fluorobenzoic acid stems from its role as a crucial intermediate in the synthesis of:

  • Pharmaceuticals: It is extensively used in the creation of Active Pharmaceutical Ingredients (APIs), particularly for anti-inflammatory, analgesic, and anti-cancer agents. Researchers often seek this compound when developing novel drugs that require specific fluorinated moieties for improved efficacy and reduced side effects.
  • Agrochemicals: The compound is a valuable precursor in the synthesis of pesticides, herbicides, and other crop protection chemicals. Its structure can contribute to the development of more potent and environmentally stable agrochemical formulations.
  • Material Science: In some instances, it finds use in the development of specialty polymers and advanced materials, where its halogen substituents can impart desirable thermal and chemical resistance properties.
  • Organic Synthesis: As a versatile building block, it is utilized in various coupling reactions and complex molecular architecture constructions by academic and industrial chemists.

For procurement managers, key considerations when looking to buy this chemical include purity, consistent batch-to-batch quality, reliable supply, and competitive pricing. R&D scientists will focus on the product's reactivity, isomer purity, and availability for scaling up laboratory syntheses.

Choosing the Right Supplier: Why China Matters

When sourcing chemical intermediates, especially those with specific purity requirements, many global companies turn to manufacturers in China due to their established infrastructure and competitive pricing. Identifying a reputable manufacturer and supplier in China for 2-Bromo-4-fluorobenzoic acid is crucial. Look for suppliers who:

  • Provide clear Certificates of Analysis (COAs) detailing purity, assay, and other critical parameters.
  • Offer robust safety data sheets (SDS) for safe handling and storage.
  • Demonstrate a track record of consistent quality and on-time delivery.
  • Have a responsive sales and technical support team ready to assist with inquiries and bulk quote requests.
  • Can offer competitive pricing, especially for bulk purchases, making them an ideal partner for large-scale manufacturing.

By understanding the product's critical role and partnering with experienced suppliers, businesses can ensure they procure high-quality 2-Bromo-4-fluorobenzoic acid efficiently, driving innovation in their respective fields. If you are looking to purchase this essential chemical intermediate, exploring options from established Chinese manufacturers can provide significant advantages in both cost and availability.