For businesses operating within the pharmaceutical sector, the consistent and reliable sourcing of high-quality chemical intermediates is paramount. Among these vital compounds is 2-Fluoro-5-nitropyridine, identified by its CAS number 456-24-6. This article aims to guide procurement managers and R&D scientists in understanding the significance of this compound and how to secure it effectively from reputable manufacturers.

Understanding 2-Fluoro-5-nitropyridine (CAS 456-24-6)

2-Fluoro-5-nitropyridine is a key heterocyclic organic compound, frequently utilized as a building block in the synthesis of various pharmaceutical drugs and agrochemicals. Its molecular formula is C5H3FN2O2, with a molecular weight of 142.09. Typically appearing as a white powder, it possesses a defined melting point range, often cited between 142-144°C. The compound's structure, featuring both a fluorine atom and a nitro group on a pyridine ring, imparts unique reactivity, making it invaluable in complex organic synthesis.

Key Applications in Pharmaceutical Development

The primary application of 2-Fluoro-5-nitropyridine lies in its role as a crucial pharmaceutical intermediate. It is instrumental in the synthesis of Active Pharmaceutical Ingredients (APIs) for a diverse range of therapeutic areas. Researchers and product formulators often seek this compound for its ability to introduce specific functional groups and structural motifs into target molecules. For instance, its nitro group can be readily reduced to an amino group, opening pathways to numerous derivatizations. Understanding these applications helps procurement professionals identify the precise specifications required for their R&D or manufacturing processes.

Navigating the Procurement Process: Finding a Reliable Supplier

When looking to buy 2-Fluoro-5-nitropyridine, the focus must be on quality, purity, and supply chain stability. Sourcing from established manufacturers, particularly those with a strong presence in China known for chemical production, is often a strategic advantage. Key considerations include:

  • Purity Levels: Ensure the supplier provides certificates of analysis (CoA) confirming purity, typically aiming for ≥99.0% for pharmaceutical applications.
  • Manufacturing Standards: Look for suppliers adhering to international quality standards like ISO 9001:2015.
  • Supply Chain Reliability: A consistent supply is critical. Evaluate the manufacturer's production capacity and track record.
  • Technical Support: A good supplier will offer technical data and support to aid in the application of their products.

For businesses seeking a dependable source for 2-Fluoro-5-nitropyridine, exploring options from reputable chemical manufacturers in China can provide both quality and cost-effectiveness. When you need to purchase this essential intermediate, prioritizing suppliers that emphasize high purity and consistent production will ensure your projects proceed without interruption.

Securing a reliable supply of 2-Fluoro-5-nitropyridine is a cornerstone for innovation in the pharmaceutical industry. By understanding its properties and applications, and by partnering with trusted manufacturers, you can confidently procure this vital component for your ongoing development needs.