For professionals in the pharmaceutical, agrochemical, and fine chemical industries, the quality and purity of starting materials are paramount. 2-Hydroxy-4-methylpyridine (CAS 13466-41-6) is one such critical intermediate that plays a significant role in the synthesis of complex molecules. Understanding its properties and applications, and knowing where to source it reliably, can significantly impact the success of your research and development projects.

What is 2-Hydroxy-4-methylpyridine?

2-Hydroxy-4-methylpyridine, also known by synonyms such as 4-Methyl-2-pyridone or 2-Hydroxy-4-picoline, is an organic compound with the molecular formula C6H7NO. Its chemical structure makes it a versatile building block for a wide array of downstream products. Its physical form is typically an off-white to yellow-brown crystalline powder, with a melting point between 131-134 °C and a boiling point of 186-187 °C at 12 mm Hg. These physical properties are vital for formulators and chemists when designing synthesis routes.

Key Applications in Synthesis

The primary value of 2-Hydroxy-4-methylpyridine lies in its utility as an intermediate. It is extensively used in:

  • Pharmaceutical Intermediates: It serves as a key precursor in the synthesis of various pharmaceutical compounds, including inhibitors of serine proteases and human leukocyte elastase, as well as analogs for corticotropin releasing factor receptor antagonists. This makes it an indispensable component for many drug discovery and manufacturing processes.
  • Pesticide Intermediates: In the agrochemical sector, this compound is employed in the creation of effective pesticides and crop protection agents. Its incorporation into larger molecules can enhance efficacy and target specificity, contributing to modern agricultural solutions.
  • Dye Intermediates: The chemical structure of 2-Hydroxy-4-methylpyridine also lends itself to the synthesis of specialized dyes, allowing for the development of unique colorants with improved properties.
  • Flavor and Fragrance Intermediates: In some applications, it can be utilized in the creation of compounds that contribute to specific flavor or fragrance profiles.

Why Purity Matters for Your Projects

When you are looking to buy 2-Hydroxy-4-methylpyridine for critical applications, purity is non-negotiable. Impurities can lead to unwanted side reactions, reduced yields, and compromised final product quality, especially in pharmaceutical synthesis where stringent regulations apply. Therefore, sourcing from a reputable 2-Hydroxy-4-methylpyridine supplier China offers significant advantages, as many Chinese manufacturers adhere to high international quality standards.

Finding a Reliable Manufacturer and Competitive Price

For businesses requiring consistent and high-quality 2-Hydroxy-4-methylpyridine, identifying a reliable manufacturer is key. Many international companies choose to purchase 2-Hydroxy-4-methylpyridine from China due to the competitive pricing and the vast manufacturing capabilities available. When seeking a CAS 13466-41-6 price, it's essential to compare offers from multiple suppliers, considering not just the cost but also the purity, packaging, and delivery terms. As a trusted pharmaceutical intermediate manufacturer, we are committed to providing exceptional value and quality.

In conclusion, 2-Hydroxy-4-methylpyridine is a foundational chemical for many advanced syntheses. By understanding its applications and prioritizing high-purity sourcing from dependable suppliers, you can ensure the success and efficiency of your ongoing projects. We invite you to request a quote and experience our commitment to quality and service.