For procurement managers and R&D scientists in the pharmaceutical industry, sourcing critical intermediates like (3,4-Dimethoxyphenyl)acetonitrile (CAS 93-17-4) is a foundational step in ensuring successful drug development and manufacturing. Understanding the key considerations when purchasing this compound can significantly impact project timelines and final product quality. This article serves as a practical guide for buyers looking to procure (3,4-Dimethoxyphenyl)acetonitrile, focusing on critical aspects such as purity, pricing, and identifying reliable manufacturers and suppliers, particularly within China.

Understanding (3,4-Dimethoxyphenyl)acetonitrile (CAS 93-17-4)

(3,4-Dimethoxyphenyl)acetonitrile, also known by synonyms such as Homoveratronitrile or Veratryl cyanide, is a chemical compound with the molecular formula C10H11NO2 and a molecular weight of 177.2. Its primary significance lies in its role as a key intermediate in the synthesis of various pharmaceuticals, most notably the antibiotic cefuroxime. Its chemical structure also lends itself to broader applications in organic synthesis, making it a versatile compound for chemical research and development.

Key Considerations for Buyers: Purity and Specifications

When purchasing (3,4-Dimethoxyphenyl)acetonitrile, the most crucial factor is its purity. For pharmaceutical applications, especially in the synthesis of Active Pharmaceutical Ingredients (APIs) like cefuroxime, high purity is paramount. Buyers should look for suppliers who can guarantee a purity level of 98% or higher, often specifying it as ≥99%. Along with purity, it's essential to review other specifications such as appearance (typically described as colorless to transparent liquid or white to off-white crystals), melting point, boiling point, and solubility. Requesting Certificates of Analysis (CoA) from potential manufacturers is a standard practice to verify these specifications and ensure they meet your project's requirements.

Navigating the Market: Price and Volume

The price of (3,4-Dimethoxyphenyl)acetonitrile can vary based on purity, quantity, and the supplier's location and manufacturing capabilities. As a buyer, obtaining multiple quotes from different manufacturers is advisable to secure a competitive price. For bulk purchases, establishing a direct relationship with a reputable Chinese manufacturer can often lead to more favorable pricing and better supply chain reliability. Understanding your projected volume needs—whether for research quantities (grams) or commercial production (kilograms to metric tons)—will help in negotiating terms and ensuring consistent supply.

Identifying Reliable Suppliers and Manufacturers

Choosing a trustworthy supplier is as important as the product's quality. When looking for (3,4-Dimethoxyphenyl)acetonitrile manufacturers, prioritize those with a proven track record in the fine chemical or pharmaceutical intermediate sector. Key indicators of reliability include:

  • Certifications: ISO certifications, GMP compliance (if applicable for your use case), and adherence to international quality standards.
  • Technical Support: Suppliers who offer robust technical support, including detailed product documentation and responsive customer service, are invaluable.
  • Supply Chain Transparency: A clear understanding of their manufacturing processes and logistics capabilities is crucial, especially for ensuring timely delivery.
  • Customer Reviews and Testimonials: Feedback from other buyers can provide insights into a supplier's performance and product consistency.

NINGBO INNO PHARMCHEM CO.,LTD. is a recognized manufacturer and supplier based in China, known for providing high-quality pharmaceutical intermediates. They focus on stringent quality control and efficient production, making them a strong candidate for buyers seeking reliable sourcing solutions for (3,4-Dimethoxyphenyl)acetonitrile. Partnering with such a supplier ensures that you receive materials that meet your exact specifications, thereby supporting the integrity and success of your downstream processes.

In conclusion, when procuring (3,4-Dimethoxyphenyl)acetonitrile, a diligent approach to verifying purity, comparing prices, and selecting a dependable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is essential. This strategic sourcing ensures you obtain a high-quality intermediate, facilitating your pharmaceutical manufacturing and R&D endeavors.