For procurement managers and R&D scientists in the chemical and pharmaceutical industries, identifying reliable sources for high-quality intermediates is a constant challenge. 3,5-Bis(trifluoromethyl)benzonitrile (CAS No.: 27126-93-8) is one such compound, critical for various synthetic processes, particularly in drug development. This guide aims to help buyers navigate the market and find the best suppliers, focusing on essential factors like purity, availability, and manufacturer credentials.

When looking to purchase 3,5-Bis(trifluoromethyl)benzonitrile, the first consideration is purity. This compound is typically specified with a minimum purity of 97% or higher, often analyzed via Gas Chromatography (GC). Higher purity levels are crucial for pharmaceutical applications, as impurities can affect reaction yields, product quality, and regulatory compliance. Reputable manufacturers will provide a Certificate of Analysis (CoA) detailing the purity and other key specifications, such as melting point (around 16°C) and boiling point (around 155°C).

The primary application driving the demand for 3,5-Bis(trifluoromethyl)benzonitrile is its use as an intermediate in the synthesis of pharmaceuticals. Its structure, featuring two trifluoromethyl groups, significantly contributes to the lipophilicity and metabolic stability of the final drug molecule. This is particularly relevant in the production of anti-cancer agents like Selinexor. For companies involved in this synthesis, securing a consistent supply of this intermediate from a trusted manufacturer is non-negotiable. Buyers often search for terms like 'buy 3,5-Bis(trifluoromethyl)benzonitrile supplier' or 'CAS 27126-93-8 price' to find suitable vendors.

Geographically, China has emerged as a major hub for the production of fine chemicals and pharmaceutical intermediates, including 3,5-Bis(trifluoromethyl)benzonitrile. Many global companies source their requirements from Chinese manufacturers due to competitive pricing and extensive production capabilities. When sourcing from China, it is essential to partner with established companies that have a proven track record in export and quality control. Look for suppliers who can provide comprehensive documentation and have strong customer support.

Beyond pharmaceuticals, 3,5-Bis(trifluoromethyl)benzonitrile is also valued in broader organic synthesis and potentially in materials science due to its unique chemical properties. Its versatility makes it a target for various research projects. For businesses looking to buy in bulk, inquiring about wholesale prices and lead times is a standard procedure. Comparing quotes from different suppliers, while always verifying the quality and reliability of the manufacturer, is a prudent approach. Ultimately, selecting a supplier that can consistently deliver high-quality 3,5-Bis(trifluoromethyl)benzonitrile at a competitive price is key to successful procurement and uninterrupted research and manufacturing operations.