In the intricate world of pharmaceutical manufacturing, the consistent availability of high-quality raw materials is paramount. One such essential compound is 3,5-Dibenzyloxyacetophenone, identified by its CAS number 28924-21-2. This chemical intermediate plays a crucial role in the synthesis of various Active Pharmaceutical Ingredients (APIs), most notably as a precursor for terbutaline. For procurement managers and R&D scientists, understanding the nuances of sourcing this compound is key to maintaining production efficiency and product integrity.

Understanding 3,5-Dibenzyloxyacetophenone

3,5-Dibenzyloxyacetophenone typically presents as an off-white to white powder. Its molecular formula is C22H20O3, with a molecular weight of approximately 332.39 g/mol. The purity of this compound is a critical factor, with specifications often requiring an assay of ≥99.0%. This high level of purity is non-negotiable when it comes to pharmaceutical applications, as impurities can significantly impact the efficacy and safety of the final drug product.

Key Applications in Pharmaceutical Synthesis

The primary utility of 3,5-Dibenzyloxyacetophenone lies in its role as a pharmaceutical intermediate. It is a vital building block in the multi-step synthesis of terbutaline, a bronchodilator used to treat asthma and other respiratory conditions. Beyond terbutaline, its structural features make it valuable in the broader field of organic synthesis, enabling the creation of complex molecules for drug discovery and development. Researchers leverage its reactive sites to construct novel chemical entities with potential therapeutic benefits.

Strategic Sourcing for Reliable Supply

For businesses looking to buy 3,5-Dibenzyloxyacetophenone, identifying a dependable manufacturer and supplier is crucial. China has emerged as a significant hub for the production of fine chemicals and pharmaceutical intermediates, offering competitive pricing and robust supply capabilities. When evaluating suppliers, it's essential to look for those who can provide detailed technical specifications, certificates of analysis (CoA), and demonstrate a consistent track record of quality control. Engaging directly with manufacturers or their authorized representatives can often lead to better pricing and a more streamlined procurement process, especially for bulk purchases.

Navigating the Market: Price and Availability

The price of 3,5-Dibenzyloxyacetophenone can fluctuate based on market demand, production costs, and order volume. For procurement managers, obtaining multiple quotes from reputable suppliers is a standard practice to ensure they are securing a competitive price. Understanding market trends and the global supply landscape can also inform purchasing decisions. For example, a reliable supplier in China can offer significant advantages in terms of cost-effectiveness and accessibility, making it a preferred choice for many global pharmaceutical companies seeking to purchase this essential intermediate.

In conclusion, 3,5-Dibenzyloxyacetophenone (CAS 28924-21-2) is an indispensable compound for the pharmaceutical industry. By focusing on purity, understanding its applications, and partnering with reputable manufacturers, procurement professionals can ensure a stable and cost-effective supply, thereby supporting the development and production of vital medications.