In the intricate world of chemical synthesis, securing high-quality raw materials is paramount. For R&D scientists and procurement managers, understanding the nuances of sourcing specialized intermediates like 3,5-Difluorophenylacetonitrile (CAS: 122376-76-5) is key to project success. This article delves into what makes this compound valuable and how to find a dependable supplier.

What is 3,5-Difluorophenylacetonitrile?

3,5-Difluorophenylacetonitrile is a vital organic synthesis intermediate, recognized for its unique difluorinated aromatic structure. Its chemical formula is C8H5F2N, and it has a molecular weight of 153.13. Typically appearing as a white to yellowish solid, it is characterized by a melting point between 35-38 °C and a boiling point around 204.4 °C. Its high purity, often exceeding 99.0%, makes it an indispensable component in complex chemical reactions.

Key Applications Driving Demand

The demand for 3,5-Difluorophenylacetonitrile is largely driven by its critical roles in two primary sectors:

  • Pharmaceuticals: It serves as a fundamental building block for a wide range of pharmaceutical agents. Researchers leverage its fluorinated structure to enhance drug efficacy, metabolic stability, and bioavailability, particularly in the development of CNS-active compounds and kinase inhibitors. When you buy 3,5-difluorophenylacetonitrile for drug discovery, you are investing in innovation.
  • Agrochemicals: In the agricultural industry, this compound is a key intermediate for synthesizing advanced pesticides and herbicides. The introduction of fluorine atoms can lead to more potent and environmentally friendly crop protection solutions. Sourcing this chemical for farm chemical production ensures higher performance and better crop safety.

Beyond these major applications, 3,5-Difluorophenylacetonitrile is also employed in various organic synthesis processes for specialty chemicals and advanced materials, making it a versatile tool for chemists.

Finding a Reliable Manufacturer and Supplier

When you need to purchase 3,5-Difluorophenylacetonitrile, selecting the right manufacturer and supplier is crucial. Consider the following factors:

  • Purity and Assay: Ensure the supplier can consistently provide material with an assay of ≥99.0% or higher, backed by Certificates of Analysis (CoA).
  • Supply Chain Stability: A reliable manufacturer in China can guarantee a consistent supply, preventing production delays and inventory shortages. Look for suppliers with established production capabilities.
  • Competitive Pricing: Directly sourcing from a manufacturer often provides better pricing compared to intermediaries. Inquire about wholesale and bulk purchase options.
  • Technical Support and Documentation: A good supplier will provide comprehensive safety data sheets (SDS), technical specifications, and responsive customer service.
  • Location and Logistics: For efficient procurement, especially when looking for a manufacturer in China, consider their shipping capabilities and lead times.

By focusing on these criteria, procurement managers can confidently secure the necessary quantities of 3,5-Difluorophenylacetonitrile, facilitating their company's research and manufacturing objectives. Whether you are looking for a price quote or need to buy in bulk, a thorough supplier evaluation is the first step.