For professionals in the pharmaceutical and fine chemical industries, sourcing reliable, high-purity chemical intermediates is a constant priority. 4,4-Difluorocyclohexanecarboxylic Acid (CAS: 122665-97-8) is one such compound, widely recognized for its utility as a building block in complex organic synthesis, particularly for pharmaceutical applications. This guide aims to equip buyers with the knowledge needed to effectively source this valuable intermediate.

The chemical structure of 4,4-Difluorocyclohexanecarboxylic Acid, featuring geminal difluorination on a cyclohexane ring, makes it an attractive moiety for introducing fluorine into target molecules. Fluorine substitution can profoundly impact a molecule's pharmacokinetic properties, such as bioavailability, metabolic stability, and lipophilicity, making it a key strategy in drug discovery and development. For instance, its use in the synthesis of Maraviroc highlights its significance in creating advanced APIs.

When looking to buy 4,4-Difluorocyclohexanecarboxylic Acid, purity is a critical factor. Manufacturers typically specify purity levels using Gas Chromatography (GC), with ≥98% being a common standard for pharmaceutical intermediates. Buyers should always request a Certificate of Analysis (CoA) to verify the purity and impurity profile of the product. Understanding the physical form, such as crystalline solid, and proper storage conditions (cool, dry, away from moisture and heat) is also essential for maintaining product integrity.

China has emerged as a significant global hub for chemical manufacturing, including advanced intermediates like 4,4-Difluorocyclohexanecarboxylic Acid. Many Chinese manufacturers offer competitive pricing and a broad range of products. For buyers, it is crucial to partner with manufacturers who not only provide high-quality products but also have robust quality management systems and reliable customer support. NINGBO INNO PHARMCHEM CO.,LTD. is an example of a supplier committed to delivering high-purity chemicals and supporting its clients' procurement needs, ensuring you can buy with confidence.