For procurement managers and R&D scientists in the pharmaceutical industry, securing a consistent supply of high-quality chemical intermediates is paramount. One such critical compound is 4-Acetyl-1-Naphthoic Acid, identified by CAS Number 131986-05-5. This chemical is a vital building block, particularly in the synthesis of veterinary drugs like Afoxolaner, a leading ectoparasiticide. Understanding where to source this intermediate effectively can significantly impact project timelines and product quality.

Understanding the Need for Quality Intermediates

The efficacy and safety of final pharmaceutical products are directly dependent on the purity and consistency of their constituent intermediates. 4-Acetyl-1-Naphthoic Acid, with its specific chemical structure (C13H10O3), is essential for creating the active pharmaceutical ingredients (APIs) used in animal health products. A reliable supplier who can guarantee high purity, often exceeding 98% or 99%, is crucial for meeting regulatory standards and achieving desired synthesis outcomes. This is where partnering with established chemical manufacturers becomes critical.

Key Applications and Synthesis Pathways

The primary industrial application for 4-Acetyl-1-Naphthoic Acid is its role as an intermediate in the production of Afoxolaner and related compounds. These are isoxazoline-class insecticides and acaricides that are highly effective against fleas and ticks in companion animals. The synthesis of these complex molecules often involves multi-step chemical processes, and the quality of intermediates like 4-Acetyl-1-Naphthoic Acid directly influences the yield and purity of the final API. Beyond veterinary medicine, its unique naphthalene core and functional groups also make it a valuable compound for various organic synthesis applications, including the development of dyes and novel materials.

Sourcing Strategies: Finding a Reliable Manufacturer in China

When looking to buy 4-Acetyl-1-Naphthoic Acid, many pharmaceutical companies turn to China for its robust chemical manufacturing capabilities and competitive pricing. Identifying reputable Chinese manufacturers and suppliers is key. Look for companies that provide detailed product specifications, Certificates of Analysis (CoA), and can offer custom synthesis services if needed. Companies with ISO and GMP certifications often demonstrate a commitment to quality control and regulatory compliance. Furthermore, a supplier’s ability to provide timely shipping and comprehensive documentation can streamline the procurement process. For those seeking to purchase this intermediate, engaging in direct inquiries about availability, minimum order quantities (MOQ), and lead times is advisable.

By focusing on quality, reliability, and competitive pricing, businesses can secure the necessary chemical intermediates like 4-Acetyl-1-Naphthoic Acid to drive their pharmaceutical development forward. Consider exploring options from NINGBO INNO PHARMCHEM CO.,LTD. for your sourcing needs.