For professionals in pharmaceutical research and development, securing reliable sources of high-purity chemical intermediates is paramount. One such compound gaining traction is 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine (CAS: 956025-83-5). This heterocyclic compound serves as a crucial building block in various synthetic pathways, particularly within drug discovery and medicinal chemistry. As a discerning buyer, understanding where and how to procure this material efficiently is key to project success. This guide aims to illuminate the process of sourcing this vital intermediate, focusing on quality, price, and supplier reliability.

Understanding the Need for High Purity
The efficacy and safety of final pharmaceutical products are directly linked to the purity of their starting materials. For 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine, a minimum purity of 97% is often specified to ensure consistent reaction outcomes and to avoid introducing undesirable impurities into complex synthetic routes. This is particularly important when the compound is intended for research in areas like kinase inhibition, where specificity and lack of off-target effects are critical.

Key Considerations When Buying
When looking to purchase 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine, several factors should guide your decision-making:

  1. Manufacturer Reputation and Reliability: Opt for established manufacturers known for their quality control and consistent production. Companies based in China have emerged as significant players in the global chemical supply chain, offering competitive advantages in both cost and scale.
  2. Product Specifications: Always verify the purity, physical form (typically white solid), and CAS number (956025-83-5) to ensure you are receiving the correct material. Details like melting point (136-138°C) and solubility characteristics can also be important for process development.
  3. Pricing and Bulk Discounts: For R&D projects or larger-scale manufacturing, understanding the price per gram and potential bulk discounts is crucial for budget management. Comparing quotes from different suppliers is a standard practice for procurement managers.
  4. Delivery and Logistics: Ensure the supplier offers reliable worldwide delivery, with options like DHL, FedEx, or UPS. Lead times and shipping costs can significantly impact project timelines.
  5. Free Samples: Many reputable manufacturers offer free samples for qualified buyers. This allows researchers to test the material's suitability for their specific applications before committing to a large purchase.

Navigating the Chinese Market for Chemical Intermediates
China has become a powerhouse for chemical manufacturing, offering a vast array of pharmaceutical intermediates at competitive prices. When sourcing 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine from China, look for suppliers who provide detailed product specifications, certificates of analysis (CoA), and responsive communication. Many Chinese chemical manufacturers are adept at handling international orders and can provide the necessary documentation and support for import and customs processes. The availability of this compound in various packaging sizes, from milligrams for initial screening to grams for pilot studies, is a testament to the flexible manufacturing capabilities present.

How to Secure Your Supply Chain
To effectively buy 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine, consider reaching out to known manufacturers and suppliers in China. Requesting a quote will provide you with current pricing and availability. By focusing on suppliers who emphasize quality, offer technical support, and demonstrate a commitment to customer satisfaction, you can build a robust and dependable supply chain for your critical research materials. Partnering with a reliable manufacturer ensures that your scientific endeavors are supported by the highest quality chemical inputs.