For procurement managers in the pharmaceutical and fine chemical industries, sourcing high-quality raw materials is paramount. Among these critical compounds is 4-Amino-3-chlorobenzoic Acid, identified by its CAS number 2486-71-7. This article aims to provide valuable insights for purchasing professionals looking to buy this essential pharmaceutical intermediate, focusing on purity, applications, and the advantages of partnering with Chinese manufacturers.

Understanding 4-Amino-3-chlorobenzoic Acid's Significance

4-Amino-3-chlorobenzoic Acid is a vital chemical building block, recognized for its role in complex organic synthesis. Its molecular structure, featuring an amino group, a chlorine atom, and a carboxylic acid group on a benzene ring, makes it a versatile intermediate. Primarily, it is utilized in the synthesis of various bioactive molecules, most notably in the development of inhibitors for specific kinases, such as MPS1. These kinase inhibitors are of significant interest in oncology research and drug development due to their potential in treating certain types of cancer. Therefore, securing a reliable supply of this compound is crucial for research and development pipelines.

Key Considerations for Procurement

When procuring 4-Amino-3-chlorobenzoic Acid, several factors are critical:

  • Purity: The purity of the chemical directly impacts the success of subsequent reactions and the quality of the final product. For pharmaceutical applications, a minimum purity of 97.0% or higher, often verified by HPLC, is typically required. When you search to buy 4-Amino-3-chlorobenzoic Acid, always check the Certificate of Analysis (CoA) for detailed purity information.
  • Physical Properties: Understanding the physical state of the chemical is important for handling and storage. 4-Amino-3-chlorobenzoic Acid is generally supplied as a white powder, with a melting point around 228°C.
  • Supplier Reliability: Partnering with a reputable manufacturer and supplier is key. Reliability encompasses consistent product quality, adherence to delivery schedules, and transparent communication. Look for suppliers with a proven track record in the fine chemical sector.

The Advantage of Sourcing from China

China has emerged as a global hub for chemical manufacturing, offering significant advantages for procurement managers. Many Chinese companies specialize in producing high-quality pharmaceutical intermediates at competitive prices. When looking for a 4-Amino-3-chlorobenzoic Acid manufacturer in China, you can expect to find companies that:

  • Operate advanced manufacturing facilities.
  • Adhere to stringent quality control standards.
  • Offer flexible order quantities, from laboratory scale to bulk industrial supply.
  • Provide competitive pricing for 4-Amino-3-chlorobenzoic Acid CAS 2486-71-7.

Engaging directly with a Chinese manufacturer can streamline the procurement process and potentially reduce costs, provided thorough due diligence is performed. Requesting samples and comparing specifications from multiple suppliers is a prudent approach.

Applications and Future Trends

Beyond its use in kinase inhibitor synthesis, 4-Amino-3-chlorobenzoic Acid can be employed in the creation of other specialty chemicals and advanced materials. As research in medicinal chemistry and materials science continues to evolve, the demand for such versatile intermediates is expected to grow. For companies looking to secure their supply of this compound, exploring partnerships with established manufacturers is a strategic move. By understanding the product's specifications and the supplier landscape, procurement managers can ensure they obtain the best value and quality for their investment.

In conclusion, when you need to buy 4-Amino-3-chlorobenzoic Acid, focus on purity, application suitability, and the reliability of your supplier. Leveraging the manufacturing strengths of Chinese companies can provide a cost-effective and quality-assured solution for your pharmaceutical intermediate needs.