For procurement managers and R&D scientists in the pharmaceutical and agrochemical sectors, sourcing high-quality intermediates is paramount. One such critical compound is 4-Amino-3-pyridinol (CAS 52334-53-9), a versatile building block with applications ranging from API synthesis to the development of advanced agrochemicals. Understanding the nuances of procuring this fine chemical intermediate can significantly impact project timelines and product efficacy.

What Makes 4-Amino-3-pyridinol a Critical Intermediate?
4-Amino-3-pyridinol, with its chemical formula C5H6N2O and molecular weight of 110.11, is recognized for its unique structure that lends itself to a variety of complex organic syntheses. Its utility as a pharmaceutical intermediate is well-documented, serving as a precursor for numerous biologically active molecules. Similarly, in the agrochemical industry, it contributes to the creation of potent and selective pesticides and herbicides, supporting advancements in crop protection. The demand for high-purity grades, typically 95% or above, underscores its importance in sensitive chemical reactions.

Key Considerations for Buyers: Purity, Supply, and Price
When looking to buy 4-Amino-3-pyridinol, several factors come into play. Firstly, purity is non-negotiable. Professionals often seek grades of 99% or higher to ensure predictable reaction outcomes and avoid by-products. Secondly, supply chain stability is crucial. Relying on a consistent manufacturer and supplier, especially from a global hub like China, ensures that your R&D or production schedules are not disrupted. Finally, price is a significant consideration for budget-conscious procurement. Securing competitive pricing, particularly for bulk purchases, is a common objective.

Navigating the Procurement Process: Tips for Success
To effectively source 4-Amino-3-pyridinol, consider the following:

  • Identify Reliable Manufacturers: Look for suppliers with a proven track record in producing fine chemical intermediates. Manufacturers based in China often offer a combination of competitive pricing and extensive production capabilities.
  • Verify Product Specifications: Always request and review detailed product specifications, including purity levels (e.g., ≥99%), CAS number (52334-53-9), and any relevant analytical data such as NMR or HPLC reports.
  • Inquire About Supply Ability: Confirm the supplier's capacity to meet your volume requirements and their typical lead times for delivery. Understanding their production capacity as a manufacturer is key.
  • Request Quotations: Obtain detailed price quotes for the required quantities, including different packaging options. Comparing offers from multiple suppliers can help in securing the best value.
  • Understand Logistics and Payment Terms: Clarify Incoterms (e.g., FOB, CFR, EXW), payment methods (T/T, L/C, PayPal), and shipping options (air, sea, courier) to ensure a smooth transaction.

By focusing on these aspects, procurement professionals can confidently source 4-Amino-3-pyridinol and other essential fine chemical intermediates, driving innovation in their respective fields. Partnering with a reputable supplier is the first step towards achieving your project goals.