For chemists and procurement specialists in the pharmaceutical and specialty chemical industries, sourcing high-quality building blocks is paramount. 4-Bromo-1-fluoro-2-iodobenzene, identified by CAS number 116272-41-4, stands out as a critical intermediate due to its unique trifunctional halogenation. This compound offers significant versatility in organic synthesis, particularly in the construction of complex molecular frameworks. Understanding its properties and identifying reliable suppliers are key steps for successful R&D and manufacturing.

The Significance of 4-Bromo-1-fluoro-2-iodobenzene in Synthesis

This halogenated benzene derivative is prized for its distinct combination of fluorine, bromine, and iodine atoms. Each halogen offers different reactivity, allowing for selective functionalization and participation in various coupling reactions, such as Suzuki, Stille, and Sonogashira couplings. These reactions are foundational in creating carbon-carbon bonds, essential for building the intricate structures found in many pharmaceuticals, agrochemicals, and advanced materials. Its role as a pharmaceutical intermediate means that consistent purity and reliable supply are non-negotiable for researchers and manufacturers aiming for reproducible results.

Key Applications and Considerations

The primary utility of 4-Bromo-1-fluoro-2-iodobenzene lies in its application as a molecular building block. It serves as a crucial starting material for synthesizing a wide array of organic compounds. Its structure makes it particularly valuable in:

  • Pharmaceutical Development: Synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Creating new crop protection agents.
  • Materials Science: Developing advanced organic electronic materials and specialty polymers.
  • Fine Chemical Production: Acting as an intermediate for other complex organic molecules.

When considering purchase, chemists often look for detailed specifications, including purity levels (typically 97% min. is desired), physical properties, and appropriate storage conditions. Keeping the compound in a cool, dry, and dark place, sealed properly, ensures its stability and reactivity.

Where to Buy and Find Manufacturers

For procurement professionals and researchers seeking a dependable source, exploring manufacturers and suppliers in China offers significant advantages, including competitive pricing and access to a broad range of chemical intermediates. When searching to buy 4-Bromo-1-fluoro-2-iodobenzene, look for suppliers who provide comprehensive product data, including CAS number (116272-41-4), chemical formula (C6H3BrFI), molecular weight (300.89), and detailed purity specifications. Many leading chemical companies in China specialize in producing these complex intermediates, catering to global markets.

It is essential to partner with a reputable 4-Bromo-1-fluoro-2-iodobenzene manufacturer that can ensure product quality and timely delivery. Utilizing platforms that list verified suppliers can help streamline the procurement process. When comparing prices, consider not only the per-unit cost but also the supplier's reputation for quality control, batch consistency, and customer service. A commitment to integrity and efficiency from your chemical synthesis reagent supplier in China will ultimately support the success of your research and development projects.

In conclusion, 4-Bromo-1-fluoro-2-iodobenzene is an indispensable component for many advanced chemical synthesis endeavors. By focusing on quality, reliability, and competitive pricing when sourcing from established manufacturers, you can ensure the efficient progression of your projects, from laboratory synthesis to larger-scale production. For those looking to purchase this vital intermediate, diligent research into suppliers and clear communication regarding your specific needs will yield the best results.