For procurement managers and R&D scientists in the pharmaceutical and agrochemical industries, sourcing high-quality chemical intermediates is a critical step in the product development lifecycle. Among these essential compounds, 4-Bromo-3-chloro-2-fluoroaniline (CAS 115843-99-7) stands out due to its versatility and the unique properties it imparts to downstream products. This article serves as a guide for buyers looking to understand the nuances of sourcing this vital chemical and the factors to consider when making a purchase.

The compound's value stems from its specific molecular structure: a benzene ring adorned with bromine, chlorine, and fluorine atoms, alongside an amino group. This halogenation pattern is key to its reactivity, enabling it to participate in a wide array of organic reactions. These include nucleophilic substitutions and various cross-coupling reactions, which are fundamental to building complex molecular architectures. Consequently, 4-Bromo-3-chloro-2-fluoroaniline is a preferred building block when synthesizing novel pharmaceutical agents or advanced agrochemical formulations.

When considering where to buy 4-Bromo-3-chloro-2-fluoroaniline, purity is paramount. For applications in drug synthesis, even trace impurities can have significant consequences on the final product's efficacy and safety profile. Therefore, it is imperative to source from a manufacturer that guarantees a high assay, typically 99.0% or higher, as indicated by its specification. Buyers should look for certificates of analysis (CoA) that detail the purity and identify any potential trace contaminants. The CAS number 115843-99-7 should always be verified to ensure the correct isomer is being procured.

The global chemical market offers numerous suppliers for this intermediate. However, choosing a reliable supplier, particularly one based in China, can offer significant advantages in terms of cost-effectiveness and scalability. When evaluating potential suppliers, several factors should be assessed:

  • Quality Assurance: Does the manufacturer have robust quality control systems in place? Can they provide detailed CoAs?
  • Production Capacity: Can the supplier meet your volume requirements, from R&D quantities to large-scale commercial production?
  • Technical Support: Does the supplier offer technical assistance regarding product specifications, handling, or custom synthesis needs?
  • Logistics and Lead Times: What are their shipping capabilities and typical lead times for delivery to your region? Understanding their global reach as a supplier in China is important.
  • Regulatory Compliance: Ensure the supplier adheres to relevant chemical manufacturing and safety regulations.

The price of 4-Bromo-3-chloro-2-fluoroaniline will naturally vary based on purity, quantity, and the supplier's location and operational efficiency. However, focusing solely on the lowest price without considering quality and reliability can lead to costly setbacks. It is advisable to obtain quotes from multiple reputable suppliers and compare not just the cost but also the overall value proposition offered.

In summary, procuring 4-Bromo-3-chloro-2-fluoroaniline (CAS 115843-99-7) requires a diligent approach. By prioritizing purity, verifying specifications, and carefully selecting a trusted manufacturer and supplier, buyers can ensure they obtain a high-quality intermediate that supports their innovation in pharmaceuticals, agrochemicals, and material science. When you are ready to purchase, remember that a strategic partnership with the right supplier is key to success.