For procurement managers and R&D scientists in the pharmaceutical and fine chemical sectors, securing a reliable supply of high-quality intermediates is paramount. One such crucial compound is 4-Fluoro-7-Azaindole (CAS 640735-23-5). This article provides an in-depth look at this important molecule and offers guidance on how to best source it from trusted manufacturers and suppliers, particularly within China.

Understanding 4-Fluoro-7-Azaindole

4-Fluoro-7-Azaindole, also known by its systematic name 4-Fluoro-1H-pyrrolo[2,3-b]pyridine, is a fluorinated heterocyclic compound. Its chemical structure makes it a valuable building block in organic synthesis, especially within the pharmaceutical industry. With a molecular formula of C7H5FN2 and a molecular weight of 136.13 g/mol, it typically presents as a white powder. Its defined chemical properties, such as a melting point of 118-120°C, necessitate specific storage conditions, often in a refrigerator, to maintain its integrity.

The Importance in Pharmaceutical Development

The pharmaceutical industry extensively uses intermediates like 4-Fluoro-7-Azaindole in the synthesis of Active Pharmaceutical Ingredients (APIs). The introduction of a fluorine atom can significantly alter a molecule's properties, such as its metabolic stability, lipophilicity, and binding affinity, making fluorinated compounds highly sought after in drug discovery. Researchers leverage these characteristics to develop new therapeutic agents with improved efficacy and safety profiles. For any scientist or procurement specialist looking to buy 4-Fluoro-7-Azaindole, understanding its role as a key intermediate is crucial for project success.

Navigating the Supply Chain: Finding a Reliable Manufacturer

When searching for a reliable 4-Fluoro-7-Azaindole manufacturer, especially from China, several factors should be considered. Firstly, confirm the supplier's adherence to quality standards, such as ISO certifications. Secondly, inquire about their production capacity and consistency to ensure they can meet your volume requirements. Requesting Certificates of Analysis (CoA) and product samples for in-house testing is a standard practice for verifying purity and quality. A reputable supplier will be transparent about their manufacturing processes and product specifications.

Key Considerations for Buyers

  • Purity: Always prioritize suppliers who guarantee high purity levels for 4-Fluoro-7-Azaindole, as this directly impacts the success of your synthesis.
  • Price: While quality is paramount, obtaining competitive pricing for 4-Fluoro-7-Azaindole is essential for cost-effective production. Compare quotes from multiple trusted vendors.
  • Supply Stability: A consistent supply is vital for uninterrupted research and manufacturing. Partner with a supplier with a proven track record of reliability.
  • Technical Support: A responsive and knowledgeable supplier can provide invaluable technical assistance, from product handling to application queries.

For those looking to purchase 4-Fluoro-7-Azaindole, engaging with experienced suppliers in China can offer significant advantages in terms of both cost and accessibility. By following these guidelines, procurement professionals can ensure they partner with a manufacturer that not only provides a critical chemical intermediate but also contributes to the efficiency and success of their R&D endeavors.