For procurement managers and R&D scientists in the pharmaceutical industry, securing a consistent supply of high-quality intermediates is paramount. One such critical intermediate is 4-Hydroxybenzylamine (CAS: 696-60-6), a key component in the synthesis of Itopride, a widely prescribed gastroprokinetic agent. Understanding the nuances of sourcing this compound can significantly impact production efficiency and final product quality.

Why 4-Hydroxybenzylamine is Essential for Itopride Synthesis

Itopride hydrochloride is a dopamine D2 receptor antagonist and acetylcholinesterase inhibitor, widely used to treat gastrointestinal disorders like functional dyspepsia. The synthesis of Itopride relies heavily on intermediates like 4-Hydroxybenzylamine. The purity and reliability of this starting material directly influence the yield and quality of the active pharmaceutical ingredient (API). Therefore, identifying a dependable 4-hydroxybenzylamine manufacturer or supplier in China is a strategic move for any pharmaceutical company.

Key Considerations When Purchasing 4-Hydroxybenzylamine

When looking to buy 4-hydroxybenzylamine, several factors should be evaluated:

  1. Purity and Assay: The technical specifications indicate that 4-Hydroxybenzylamine should have an assay of ≥98.0%. Sourcing from a manufacturer that provides a Certificate of Analysis (CoA) detailing purity is essential.
  2. Physical Properties: The compound typically appears as a brown-yellow crystalline powder. Consistency in appearance and physical form is a good indicator of product quality.
  3. Supplier Reliability: For critical pharmaceutical intermediates, a stable supply chain is non-negotiable. Researching the manufacturer's production capacity, quality control processes, and delivery track record is crucial. Many international buyers seek 4-hydroxybenzylamine wholesale from established chemical suppliers.
  4. Pricing and Quotation: Obtaining a competitive price for 4-hydroxybenzylamine is important for cost management. Engaging with suppliers for direct quotes ensures you are getting the best value for your investment.

Navigating the Market: Finding the Right Supplier

The global market offers numerous options for sourcing chemical intermediates. However, for critical pharmaceutical components, partnering with manufacturers who specialize in fine chemicals and intermediates is recommended. Companies that can provide detailed technical data, regulatory support, and consistent product quality are preferred. Looking for terms like “4-hydroxybenzylamine supplier China” can lead you to reliable sources.

By prioritizing purity, reliability, and transparent pricing, pharmaceutical companies can secure a stable supply of 4-Hydroxybenzylamine, ensuring the efficient and high-quality production of Itopride. For those seeking to purchase 4-hydroxybenzylamine for their synthesis needs, a proactive approach to supplier selection is key.