For procurement managers in the B2B chemical and pharmaceutical sectors, securing reliable sources for key intermediates like 5-Bromo-2-methylaniline (CAS: 39478-78-9) is paramount. This compound, also known by synonyms such as 2-amino-4-bromotoluene, is a cornerstone ingredient in the synthesis of a wide array of critical products, from life-saving pharmaceuticals to advanced agrochemicals and vibrant dyes. Understanding its sourcing requirements, quality specifications, and application versatility is crucial for informed purchasing decisions.

Understanding 5-Bromo-2-methylaniline: Properties and Applications

5-Bromo-2-methylaniline is a halogenated aromatic amine characterized by its chemical formula C7H8BrN and CAS number 39478-78-9. Its physical form is typically described as a clear yellow to brown liquid after melting, with a melting point around 33°C. The compound's real value lies in its bifunctional nature, boasting both a reactive amino group and a bromine atom on an aromatic ring, making it an exceptionally versatile building block in organic synthesis. Its primary applications include:

  • Pharmaceutical Intermediates: It is a critical precursor for synthesizing complex drug molecules, such as Bruton's tyrosine kinase (BTK) inhibitors and activators of Sirtuin 6 (SIRT6), which are vital in treating cancers and autoimmune diseases.
  • Agrochemicals: Used in the production of fungicides and herbicides, contributing to enhanced crop protection and agricultural productivity.
  • Dyes and Pigments: Serves as a key intermediate in the synthesis of azo dyes, providing essential components for the coloration industry.
  • Material Science: Its structure is incorporated into advanced fluorescent materials for OLEDs and other specialty applications.

Key Considerations for Sourcing and Quality Assurance

When sourcing 5-Bromo-2-methylaniline, procurement professionals must prioritize purity and consistency. High-purity grades, often exceeding 97% as confirmed by GC analysis, are essential for ensuring predictable reaction outcomes and the quality of the final product. Key quality parameters to verify include:

  • Purity: Typically >97% by GC.
  • Appearance: Clear yellow to brown liquid after melting.
  • CAS Number: 39478-78-9, a unique identifier for reliable product identification.
  • Supplier Reputation: Partnering with reputable manufacturers or suppliers who provide Certificates of Analysis (CoA) is crucial.

Navigating the Market: Finding a Reliable Manufacturer

The global market offers numerous suppliers for 5-Bromo-2-methylaniline. However, for critical B2B applications, it is imperative to partner with established manufacturers who can guarantee consistent quality, competitive pricing, and reliable supply chains. Look for suppliers who:

  • Have a proven track record in manufacturing fine chemical intermediates.
  • Offer detailed technical specifications and CoAs for their products.
  • Can provide product samples for validation.
  • Maintain robust quality control processes.
  • Are transparent about their manufacturing capabilities and capacity.

As a leading manufacturer and supplier of 5-Bromo-2-methylaniline in China, we are committed to meeting these stringent requirements. We understand the critical role this intermediate plays in your operations and strive to be your preferred partner for high-quality chemical sourcing. For inquiries on price and to request a sample, please contact our sales team.