For pharmaceutical companies engaged in the synthesis of critical medications, the quality and reliability of raw materials are paramount. 5-Nitrovanillin, identified by CAS number 6635-20-7, stands out as a vital intermediate, particularly in the production of Entacapone, a key drug used in the treatment of Parkinson's disease. Understanding the procurement landscape for this chemical is essential for ensuring consistent production and product efficacy.

5-Nitrovanillin, also known chemically as 4-hydroxy-3-methoxy-5-nitrobenzaldehyde, is a yellow crystalline powder characterized by its high purity, typically assaying at ≥98.0%. Its physical and chemical properties, including a melting point of 172-175 °C, make it a stable and manageable compound for complex organic synthesis. For procurement managers and R&D scientists, sourcing this intermediate from reputable manufacturers is key to achieving desired product specifications.

When considering where to buy 5-Nitrovanillin, focusing on suppliers in China can offer significant advantages. Chinese manufacturers have established robust production capabilities and often provide competitive pricing for pharmaceutical intermediates. It is advisable to partner with suppliers who can demonstrate a strong commitment to quality control, providing certificates of analysis (CoA) and ensuring batch-to-batch consistency. This diligence is crucial to avoid costly production delays or product quality issues.

For those looking to purchase 5-Nitrovanillin, understanding its application is key. Its role as an intermediate for Entacapone means that its purity directly impacts the final API. Therefore, inquiring about supplier credentials, manufacturing practices, and adherence to international quality standards is a necessary step. Companies seeking to buy 5-Nitrovanillin should also look for suppliers who offer flexible packaging options and reliable logistics to meet their production schedules.

In summary, securing a dependable supply of high-purity 5-Nitrovanillin (CAS 6635-20-7) is a strategic imperative for pharmaceutical manufacturers. By focusing on key characteristics like assay, appearance, and by partnering with trusted manufacturers and suppliers in China, companies can ensure the quality and efficiency of their Entacapone production, ultimately benefiting patients who rely on these essential treatments.