For professionals in the pharmaceutical industry, the reliable sourcing of high-purity chemical intermediates is paramount. One such critical compound is 6-Chloro-5-(2-chloroethyl)oxindole (CAS No.: 118289-55-7). This molecule serves as a vital building block, most notably in the synthesis of Ziprasidone Hydrochloride, an essential medication for treating certain mental health conditions. Understanding its properties, applications, and how to secure a dependable supply is crucial for procurement managers, R&D scientists, and formulation chemists.

Understanding 6-Chloro-5-(2-chloroethyl)oxindole

This specific oxindole derivative is characterized by its distinct chemical structure, featuring chlorine atoms and a chloroethyl group attached to the indole ring. Its physical form is typically a pink to off-white solid, a key visual indicator of quality. The specified purity is usually ≥99.0%, with stringent limits on loss on drying (≤1%) and related impurities. These precise specifications are not merely technical details; they directly impact the efficiency and success of subsequent synthesis steps. For instance, a high-purity intermediate minimizes side reactions and ensures that the final Active Pharmaceutical Ingredient (API) meets rigorous pharmaceutical standards. When looking to buy this intermediate, always verify these specifications.

The Crucial Role in Ziprasidone Hydrochloride Synthesis

The primary application driving the demand for 6-Chloro-5-(2-chloroethyl)oxindole is its indispensable role as an intermediate in the production of Ziprasidone Hydrochloride. Ziprasidone is an atypical antipsychotic used to manage schizophrenia and bipolar disorder. The synthesis pathway requires this specific chloro-substituted oxindole to construct the core heterocyclic structure of the drug. Consequently, securing a consistent and high-quality supply of this intermediate directly influences the availability and cost-effectiveness of this important therapeutic agent. When exploring purchase options, consider manufacturers with a proven track record in supplying intermediates for established APIs.

Navigating the Procurement Process: Finding a Reliable Supplier

For businesses seeking to purchase 6-Chloro-5-(2-chloroethyl)oxindole, partnering with a reputable manufacturer or supplier is key. Several factors should be considered:

  • Quality Assurance: Look for suppliers who provide detailed Certificates of Analysis (CoA) that clearly state purity, impurity profiles, and physical properties. This documentation is your assurance of product quality.
  • Manufacturing Capabilities: A manufacturer that integrates production and trading often offers better control over quality and supply chain stability. They can also provide competitive pricing for bulk orders.
  • Regulatory Compliance: While this is an intermediate, suppliers who understand pharmaceutical industry standards and can provide necessary documentation are highly valuable.
  • Technical Support: A good supplier will offer technical support to assist with any queries related to the product's application or handling.
  • Global Reach: For international buyers, a supplier with experience in global logistics and export procedures is essential to ensure timely delivery and adherence to import regulations.

When searching for a supplier, using targeted keywords like 'buy 6-Chloro-5-(2-chloroethyl)oxindole,' '118289-55-7 intermediate price,' or 'Ziprasidone intermediate manufacturer China' can help pinpoint relevant manufacturers. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a leading manufacturer and supplier, offering high-purity pharmaceutical intermediates to meet the evolving needs of the global pharmaceutical market. We strive to provide excellent product quality, competitive pricing, and reliable service to our valued customers worldwide.