For procurement managers and research scientists operating at the forefront of chemical and pharmaceutical innovation, securing high-purity amino acid derivatives is a cornerstone of successful projects. Fmoc-N-methyl-O-tert-butyl-L-tyrosine (CAS: 133373-24-7), often referred to as Fmoc-N-Me-Tyr(tBu)-OH, is a prime example of such a critical compound. As a leading supplier and manufacturer, we are committed to providing clear, actionable information to help our B2B clients make informed purchasing decisions. This article offers insights into the importance of sourcing this specific derivative for peptide synthesis and drug discovery.

The synthesis of peptides, particularly for therapeutic applications, demands intermediates of exceptional quality and purity. Fmoc-N-Me-Tyr(tBu)-OH serves as a specialized building block in this process. Its structure is designed to facilitate efficient coupling reactions in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) group is a standard and reliable protecting group for the alpha-amino group, known for its mild removal conditions. The addition of an N-methyl group and an O-tert-butyl group on the tyrosine side chain further refines its properties. The N-methyl modification can impact peptide conformation and stability, while the O-tert-butyl group acts as a robust protecting group for the phenolic hydroxyl, essential during synthesis.

When procurement professionals evaluate suppliers for Fmoc-N-Me-Tyr(tBu)-OH, several factors are paramount: guaranteed purity levels (typically ≥98.0%), consistent batch-to-batch quality, reliable delivery, and competitive pricing. A reliable manufacturer like ourselves understands that any deviation in these parameters can significantly impact the outcomes of complex research or large-scale production runs. The purity ensures that side reactions are minimized, and purification steps are more straightforward, saving valuable time and resources.

For researchers involved in drug discovery, particularly those working on peptide-based pharmaceuticals, the availability of this derivative is crucial. It enables the precise incorporation of modified tyrosine residues into peptide sequences, allowing for the development of peptides with enhanced pharmacokinetic profiles or novel biological activities. We encourage R&D scientists to buy Fmoc-N-Me-Tyr(tBu)-OH from us to leverage its unique structural benefits for their innovative projects. Interested parties are invited to request a quote for bulk purchases to secure their supply needs.

The global supply chain for high-quality chemical intermediates is competitive. However, choosing a supplier that prioritizes scientific integrity and customer support is key. Our role as a trusted supplier goes beyond just fulfilling orders; we aim to support your research and development objectives by providing the essential building blocks you need. Whether you are developing novel therapeutics, custom peptides, or exploring new frontiers in biochemistry, ensuring a consistent and high-quality source for compounds like Fmoc-N-Me-Tyr(tBu)-OH is vital.

In summary, Fmoc-N-methyl-O-tert-butyl-L-tyrosine is a high-value amino acid derivative essential for advanced chemical synthesis and pharmaceutical development. We invite you to partner with us, a dedicated manufacturer and supplier, to purchase this critical material. Contact us today to get a quote and discuss how we can meet your specific requirements for purity, volume, and timely delivery.