For procurement managers and R&D scientists in the pharmaceutical and biotechnology sectors, sourcing high-quality chemical building blocks is paramount. Fmoc-L-2-(3-Thienyl)-glycine, with its unique thienyl side chain and Fmoc protection, is a valuable compound increasingly utilized in peptide synthesis and the development of novel pharmaceutical intermediates. Understanding how to effectively source this specialized amino acid derivative is crucial for ensuring project success and cost-efficiency.

Understanding the Product: Fmoc-L-2-(3-Thienyl)-glycine

Fmoc-L-2-(3-Thienyl)-glycine (CAS 372143-96-9) is a non-proteinogenic amino acid derivative. The Fmoc (9-fluorenylmethyloxycarbonyl) group serves as a base-labile protecting group for the alpha-amino function, essential for controlled solid-phase peptide synthesis (SPPS). The presence of the 3-thienyl group introduces a heterocyclic moiety into the peptide chain, which can impart unique physicochemical properties and biological activities. Researchers often look for this compound when synthesizing peptides designed for specific therapeutic applications or as part of drug discovery programs.

Key Considerations for Sourcing Managers

When looking to buy Fmoc-L-2-(3-Thienyl)-glycine, several factors must be meticulously evaluated:

  1. Purity: The purity of the amino acid derivative directly impacts the success of peptide synthesis. High purity, typically 98.0% or greater as determined by HPLC, is essential to minimize side reactions and ensure the integrity of the final peptide product. Reputable manufacturers will provide Certificates of Analysis (CoA) detailing purity and other critical specifications.
  2. Supplier Reliability: Establishing a relationship with a reliable manufacturer and supplier is key. Consider suppliers with a proven track record in producing and supplying specialized amino acids and pharmaceutical intermediates. Look for suppliers who can offer consistent batch-to-batch quality and robust supply chain management, especially for bulk purchases.
  3. Pricing and Bulk Orders: For larger research projects or commercial manufacturing, obtaining competitive pricing for bulk orders is important. Engaging directly with manufacturers in regions like China, known for their chemical synthesis capabilities, can often lead to significant cost savings without compromising on quality. Always request a formal quote for your specific volume requirements.
  4. Technical Support and Documentation: A good supplier will offer comprehensive technical support, including safety data sheets (SDS) and detailed product specifications. This information is vital for researchers and safety officers within your organization.

Why NINGBO INNO PHARMCHEM is Your Ideal Partner

NINGBO INNO PHARMCHEM CO.,LTD. stands as a dedicated manufacturer and supplier of high-quality chemical products, including specialized amino acid derivatives like Fmoc-L-2-(3-Thienyl)-glycine. We understand the stringent demands of the pharmaceutical and research industries. Our commitment to purity, coupled with our efficient manufacturing processes in China, allows us to offer this critical building block at competitive prices. We serve procurement managers globally, providing them with the reliable sourcing solutions they need to advance their projects. Whether you are looking for small quantities for initial research or bulk supply for larger-scale synthesis, we are equipped to meet your demands. Contact us today to learn more about our product offerings and to secure your supply of Fmoc-L-2-(3-Thienyl)-glycine.