Sourcing High-Purity Iohexol Intermediate: A Buyer's Guide
For professionals in the pharmaceutical and chemical industries, sourcing critical raw materials is a task that demands precision, reliability, and an understanding of market dynamics. One such essential compound is 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, identified by its CAS number 31127-80-7. This chemical is a cornerstone in the production of Iohexol, a widely used non-ionic contrast agent vital for diagnostic imaging. When embarking on the purchase of this specialized intermediate, buyers need a clear strategy to ensure they are acquiring a product that meets stringent quality requirements and is supplied by a dependable manufacturer.
The primary consideration for any buyer is the purity of the compound. For pharmaceutical intermediates, especially those used in contrast media, impurities can have significant implications for the efficacy and safety of the final drug product. Therefore, it is crucial to source from suppliers who can provide detailed certificates of analysis (CoA) that clearly outline the purity levels and any detected impurities. Many reputable manufacturers, particularly those operating in China, offer high-purity grades of this Iohexol intermediate, often exceeding 97% or even 98%. Understanding the product specifications, such as melting point (typically around 274-276°C) and solubility, is also important for integration into your existing synthesis processes. Engaging with a known manufacturer and supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to these critical details and a consistent product.
Beyond quality, supply chain reliability is paramount. Pharmaceutical production often operates on tight schedules, and delays in raw material delivery can have cascading effects. Buyers should look for suppliers with established production capacities and a proven track record of timely delivery. Factors such as packaging, storage conditions (often requiring 2-8°C storage due to its hygroscopic nature), and shipping logistics should also be considered. Requesting samples before placing large orders is a standard practice that allows you to verify the material's quality and suitability for your specific application. Building a relationship with a trusted supplier can lead to better pricing, particularly for bulk purchases, and provide a stable foundation for your manufacturing operations. For those looking to buy this essential pharmaceutical intermediate, a thorough evaluation of potential suppliers, focusing on their commitment to quality, manufacturing capabilities, and customer service, is a wise investment.
In summary, sourcing 5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide (CAS 31127-80-7) requires careful attention to purity, supplier reputation, and logistical considerations. By partnering with experienced chemical manufacturers and suppliers who understand the demands of the pharmaceutical industry, you can secure a vital component for the production of life-saving diagnostic agents.
Perspectives & Insights
Bio Analyst 88
“Buyers should look for suppliers with established production capacities and a proven track record of timely delivery.”
Nano Seeker Pro
“Factors such as packaging, storage conditions (often requiring 2-8°C storage due to its hygroscopic nature), and shipping logistics should also be considered.”
Data Reader 7
“Requesting samples before placing large orders is a standard practice that allows you to verify the material's quality and suitability for your specific application.”