For research scientists, process chemists, and procurement managers, the acquisition of high-purity chemical intermediates is fundamental to project success. N-Benzyloxycarbonyl-L-aspartic Acid (CAS 1152-61-0), commonly known as Z-Asp-OH or Cbz-Asp-OH, is one such critical compound, widely used in peptide synthesis, organic synthesis, and as a pharmaceutical intermediate. This guide aims to provide insights into sourcing this essential molecule, with a particular focus on the advantages of partnering with China-based manufacturers and suppliers.

Understanding N-Benzyloxycarbonyl-L-aspartic Acid

N-Benzyloxycarbonyl-L-aspartic Acid is a derivative of L-aspartic acid, featuring a benzyloxycarbonyl (Cbz) protecting group. This group is crucial for its application in controlled synthesis, preventing undesired reactions and ensuring stereochemical integrity. Its typical appearance is a white fine crystalline powder, and it is valued for its high purity, often specified at 99% or greater. The CAS number 1152-61-0 is its universal identifier, essential for accurate ordering and regulatory compliance.

Key Applications Driving Demand

The primary drivers for N-Benzyloxycarbonyl-L-aspartic Acid demand include:

  • Peptide Synthesis: As a protected amino acid, it's a cornerstone for building complex peptide chains through solid-phase or solution-phase methods.
  • Organic Synthesis: It serves as a chiral building block for creating sophisticated organic molecules, including chiral catalysts and pharmaceuticals.
  • Pharmaceutical Intermediates: It’s frequently used in the synthesis pathways of various APIs and drug candidates.

Why Source from China?

China has become a global powerhouse for chemical manufacturing, offering:

  • Cost-Effectiveness: Competitive pricing due to economies of scale and efficient production processes.
  • High Purity Standards: Many manufacturers adhere to international quality standards, offering products with 99%+ purity.
  • Extensive Supplier Network: A wide range of manufacturers and suppliers cater to diverse needs, from small research quantities to bulk industrial orders.
  • Streamlined Logistics: Established export infrastructure facilitates efficient global shipping.

How to Buy N-Benzyloxycarbonyl-L-aspartic Acid from China: A Practical Approach

When looking to purchase this chemical, consider the following steps:

  1. Identify Reputable Manufacturers/Suppliers: Look for companies with clear product specifications, positive customer reviews, and established online presences. Terms like 'manufacturer,' 'supplier,' and 'wholesale' are key search terms.
  2. Request Quotations (RFQ): Clearly specify the required quantity, purity, and any special packaging needs. Ask for the latest price and lead time.
  3. Verify Quality: Always request a Certificate of Analysis (CoA) for each batch to confirm purity and specifications. Sample testing might also be advisable for critical applications.
  4. Check Logistics and Terms: Understand Incoterms (FOB, CIF, etc.), payment terms (L/C, T/T), and shipping methods to ensure smooth delivery.
  5. Build Relationships: Long-term partnerships with reliable suppliers can offer greater stability and potentially better pricing over time.

By following these guidelines, procurement professionals can effectively source high-quality N-Benzyloxycarbonyl-L-aspartic Acid (CAS 1152-61-0) from China, securing a vital component for their synthesis projects and ensuring the success of their research and development endeavors.