For procurement managers in the pharmaceutical and fine chemical industries, securing a consistent and high-quality supply of essential intermediates is paramount. Trimethylsulfoxonium Iodide (CAS 1774-47-6) is one such compound, playing a crucial role in the synthesis of vital pharmaceuticals like fluconazole and in various organic transformations, particularly in epoxide formation. Understanding the nuances of sourcing this chemical from manufacturers in China is key to maintaining efficient operations and cost-effectiveness.

Understanding Trimethylsulfoxonium Iodide's Role

Trimethylsulfoxonium Iodide is recognized for its utility as a methylene transfer reagent. This means it efficiently donates a methylene group (CH2) to other molecules, a fundamental reaction in organic synthesis. Its primary application highlighted in the industry is its use in the synthesis of fluconazole, a widely prescribed antifungal medication. Beyond this, its ability to facilitate the formation of epoxides from ketones and aldehydes makes it invaluable for chemists developing new chemical entities or optimizing existing synthetic routes. As a 'white powder' product, its physical form is convenient for handling and integration into various reaction setups.

Key Considerations for Procurement

When looking to buy Trimethylsulfoxonium Iodide, procurement managers should prioritize several factors:

  • Purity: The article consistently mentions 'High Purity' and specifications exceeding 99%. For pharmaceutical applications, this level of purity is non-negotiable to ensure the efficacy and safety of the final drug product. Always request a Certificate of Analysis (CoA) that validates the purity and other key specifications.
  • Supplier Reliability: Establishing a relationship with a dependable manufacturer or supplier in China is crucial. Look for suppliers with established GMP, ISO certifications, and a proven track record of consistent supply and quality control. Information regarding production capacity (e.g., 2000kg/Month) can indicate a supplier's ability to meet larger volume demands.
  • Pricing and MOQ: While quality is paramount, competitive pricing is also a significant factor. Understanding the Minimum Order Quantity (MOQ), often around 1kg, and the price range (e.g., US$60.00 - 80.00 per kg) helps in budget planning. Requesting a sample is often a good first step before committing to a large purchase.
  • Application Versatility: Confirming the chemical's suitability for your specific needs, whether it's for fluconazole synthesis, epoxide formation, or other specialized reactions, is essential. The technical specifications and application notes provided by the supplier offer valuable insights.

Navigating the Supply Chain

The chemical industry, particularly for pharmaceutical intermediates, relies on robust global supply chains. China has emerged as a significant player in the manufacturing of these crucial compounds. By diligently vetting suppliers and understanding the product specifications, procurement professionals can successfully purchase Trimethylsulfoxonium Iodide and other necessary reagents. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a reliable partner, offering high-quality chemical intermediates with transparent pricing and dependable delivery, ensuring your research and production needs are met efficiently.