Sourcing High-Quality 2-Amino-3-fluorobenzoic Acid for Pharma Synthesis
For procurement managers and R&D scientists in the pharmaceutical industry, sourcing high-quality chemical intermediates is paramount. One such critical compound is 2-Amino-3-fluorobenzoic Acid, identified by CAS Number 825-22-9. This fluorinated aromatic compound serves as a fundamental building block in the synthesis of numerous active pharmaceutical ingredients (APIs), making its reliable supply a key concern for manufacturers worldwide.
Understanding the properties of 2-Amino-3-fluorobenzoic Acid is the first step for any buyer. Typically appearing as a white to light yellow crystalline powder, it boasts a purity often exceeding 98%, which is essential for the rigorous standards of pharmaceutical development. Its molecular formula is C7H6FNO2, with a molecular weight of 155.13. The melting point, generally around 171-172°C, is another critical parameter for handling and reaction planning.
When considering to buy 2-Amino-3-fluorobenzoic Acid, identifying a trustworthy manufacturer and supplier is crucial. China has emerged as a significant hub for chemical production, offering competitive pricing and a vast network of suppliers. For procurement professionals seeking to secure their supply chain, looking for manufacturers with a strong track record in producing high-purity intermediates like 3-Fluoroanthranilic Acid (an alternative name) is advisable. These suppliers often provide certificates of analysis (COAs) detailing the exact specifications, including purity and any trace impurities, ensuring transparency and quality assurance.
The applications of 2-Amino-3-fluorobenzoic Acid are diverse within the pharmaceutical sector. It is frequently used in the synthesis of heterocyclic compounds, which are core structures in many drug molecules. Its fluorinated nature can impart unique pharmacokinetic properties to the final drug, such as increased metabolic stability or improved bioavailability. Research chemists often utilize this compound in multi-step syntheses, where its reactivity and structural features can be strategically exploited to build complex molecular architectures.
For those looking to purchase 2-Amino-3-fluorobenzoic Acid in bulk, inquiring about pricing and lead times from multiple suppliers is a standard procurement practice. Many Chinese manufacturers offer significant price advantages for larger quantities, and some may even provide custom synthesis services for specific purity requirements or derivative products. Establishing a direct relationship with a reputable supplier can lead to better pricing, guaranteed quality, and consistent delivery, which are all vital for keeping pharmaceutical production on schedule and within budget.
In conclusion, 2-Amino-3-fluorobenzoic Acid (CAS:825-22-9) is an indispensable intermediate for the pharmaceutical industry. By focusing on reputable manufacturers and suppliers, understanding its key properties, and inquiring about bulk purchase options, procurement managers can ensure a stable and cost-effective supply for their critical synthesis needs. This strategic sourcing approach is key to driving innovation and success in drug development.
Perspectives & Insights
Nano Explorer 01
“The applications of 2-Amino-3-fluorobenzoic Acid are diverse within the pharmaceutical sector.”
Data Catalyst One
“It is frequently used in the synthesis of heterocyclic compounds, which are core structures in many drug molecules.”
Chem Thinker Labs
“Its fluorinated nature can impart unique pharmacokinetic properties to the final drug, such as increased metabolic stability or improved bioavailability.”