For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing high-quality chemical intermediates is paramount to successful product development and manufacturing. One such critical intermediate is N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, commonly known by its acronym EEDQ, with CAS number 16357-59-8. Understanding its properties, applications, and reliable sourcing channels is key to optimizing your supply chain and ensuring product efficacy. This guide aims to provide essential insights for buyers seeking to purchase this vital compound.

Understanding EEDQ (CAS 16357-59-8): Properties and Applications

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline is a valuable chemical reagent primarily recognized for its role in synthetic chemistry. Its molecular formula is C14H17NO3, with a molecular weight of approximately 247.29 g/mol. Typically appearing as a white to pale yellow solid, EEDQ boasts a high purity, often exceeding 98% as verified by HPLC. This purity is critical for its applications in sensitive fields such as pharmaceutical synthesis, drug discovery, and process R&D. It functions as a coupling reagent, particularly noted for its ability to facilitate peptide synthesis with minimal racemization, making it an indispensable tool for medicinal chemists.

Beyond peptide synthesis, EEDQ finds utility in various organic transformations. Its role as a chemical intermediate means it's a building block for more complex molecules, contributing to the development of novel compounds with potential therapeutic or industrial applications. Researchers exploring new chemical entities or optimizing existing synthesis routes often turn to reliable suppliers for EEDQ.

Key Considerations When Purchasing EEDQ

When looking to buy N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, several factors should guide your decision. Firstly, purity is non-negotiable. Always seek suppliers that provide certificates of analysis (CoA) detailing the purity, typically measured by HPLC or GC, and confirming the absence of critical impurities. Secondly, consider the physical form and packaging, ensuring it aligns with your storage and handling capabilities. Thirdly, understand the supplier's capacity for consistent supply, especially if you anticipate large-scale procurement for manufacturing. Reliable manufacturers often offer technical support and detailed product datasheets.

For procurement managers prioritizing cost-effectiveness without compromising quality, identifying reputable manufacturers and suppliers in China can offer significant advantages. Chinese chemical manufacturers have established robust production capabilities and stringent quality control measures, providing globally competitive pricing. When inquiring about price, it's advisable to request quotes for different quantities, as bulk purchases often come with substantial discounts.

Where to Find Reliable EEDQ Suppliers in China

Navigating the global chemical market can be complex, but focusing on established suppliers known for their reliability and quality is crucial. When searching for a supplier in China that offers N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, look for companies with a proven track record in producing and exporting fine chemicals and pharmaceutical intermediates. Companies that clearly list their CAS number (16357-59-8), provide detailed product specifications, and offer responsive customer service are generally reliable partners. Engaging directly with these manufacturers can provide access to competitive pricing and ensure a stable supply chain for your ongoing projects.

In conclusion, securing a dependable source for N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline is vital for any organization involved in pharmaceutical research and development or advanced chemical synthesis. By focusing on quality, reliable suppliers, and competitive pricing, you can ensure the success of your projects and contribute to the advancement of chemical innovation.