For professionals in the pharmaceutical and chemical industries, sourcing high-quality raw materials is paramount to success. Among these critical components, protected amino acids play a vital role, particularly in peptide synthesis and drug development. This guide focuses on Fmoc-Lys(Boc)(isopropyl)-OH (CAS 201003-48-7), a specialized derivative of lysine, and provides insights for procurement managers and research scientists seeking to buy this compound.

Understanding Fmoc-Lys(Boc)(isopropyl)-OH

Fmoc-Lys(Boc)(isopropyl)-OH, also known as N-Fmoc-N'-Boc-N'-isopropyl-L-lysine, is a protected form of lysine widely used in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethyloxycarbonyl) group offers base-labile protection for the alpha-amino group, while the Boc (tert-butyloxycarbonyl) and isopropyl groups provide orthogonal protection for the epsilon-amino group of lysine. This specific protection strategy is crucial for controlled and efficient peptide chain elongation, enabling the synthesis of complex and long peptides.

Key Applications in Research and Development

The primary application of Fmoc-Lys(Boc)(isopropyl)-OH lies in its role as a building block in the synthesis of therapeutic peptides. These peptides can range from simple sequences to highly modified structures used in various fields, including:

  • Drug Discovery: Synthesizing peptide-based therapeutics for conditions like cancer, diabetes, and autoimmune diseases.
  • Biotechnology: Developing peptide antigens for vaccines or diagnostic tools.
  • Materials Science: Creating peptide-based biomaterials or functional polymers.

Beyond peptide synthesis, it also serves as an intermediate in broader organic synthesis pathways for novel chemical entities, making it a valuable compound for research laboratories and chemical manufacturers alike.

Sourcing Strategies: Finding a Reliable Supplier

When looking to buy Fmoc-Lys(Boc)(isopropyl)-OH, several factors are critical for procurement managers and research scientists. Identifying a reputable manufacturer and supplier ensures not only product quality but also supply chain reliability and competitive pricing. Key considerations include:

  • Purity and Specifications: Always request a Certificate of Analysis (CoA) to verify the purity (typically ≥97% or ≥99.0%) and ensure it meets your specific application requirements.
  • Manufacturing Capabilities: Look for suppliers with robust manufacturing processes and quality control systems. Companies specializing in pharmaceutical intermediates and fine chemicals are often ideal.
  • Supply Chain Stability: A consistent and reliable supply is crucial for ongoing research and production. Consider manufacturers with established production capacities and logistics.
  • Customer Support and Technical Assistance: A supplier that offers good customer service and technical support can be invaluable, especially for custom synthesis inquiries or troubleshooting.
  • Price and Value: While price is a factor, it should be balanced with quality and reliability. Obtaining quotes from multiple suppliers can help determine the best market value.

Navigating the Market: China as a Key Sourcing Hub

China has emerged as a significant global hub for the manufacturing of fine chemicals and pharmaceutical intermediates. Many Chinese manufacturers offer high-quality Fmoc-Lys(Boc)(isopropyl)-OH at competitive prices. When engaging with a Chinese supplier, it's beneficial to work with established companies that have a proven track record and understand international quality standards. For instance, manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing essential chemical building blocks to the global market.

Inquiry and Next Steps

If your research or production demands high-purity Fmoc-Lys(Boc)(isopropyl)-OH, we encourage you to reach out. As a leading manufacturer and supplier, we are committed to supporting your projects with superior products and excellent service. Contact us today to request a quote, inquire about bulk purchase options, or discuss your specific needs. Partner with a trusted source for your pharmaceutical intermediate requirements.