For procurement professionals and researchers in the chemical and pharmaceutical industries, sourcing reliable and high-purity chemical compounds is a constant challenge. N-Tosyl-L-arginine (CAS 1159-15-5), a crucial amino acid derivative, is frequently required for applications ranging from peptide synthesis to biochemical assays and drug discovery. This guide focuses on how to effectively source this compound, particularly from China, emphasizing quality, pricing, and supplier selection.

Understanding the Demand for N-Tosyl-L-arginine

N-Tosyl-L-arginine, often abbreviated as Tos-Arg-OH, is valued for its role as a key reagent in organic synthesis, specifically in solid-phase peptide synthesis (SPPS). Its tosyl protecting group ensures efficient and controlled addition of arginine residues into peptide chains, leading to higher yields and purity of the final peptide product. Beyond peptide synthesis, its utility as an enzyme inhibitor, particularly for proteases, makes it indispensable in biochemical research and drug development efforts aimed at understanding enzymatic pathways and designing targeted therapies.

Key Considerations When Buying N-Tosyl-L-arginine

When making a purchase decision for N-Tosyl-L-arginine (CAS 1159-15-5), several factors are critical:

  • Purity: For research and pharmaceutical applications, high purity (typically >98%) is essential. Always request a Certificate of Analysis (CoA) to verify the product's specifications.
  • Supplier Reputation: Partner with established manufacturers and suppliers who have a proven track record in delivering consistent quality.
  • Pricing: While cost is always a factor, it should be balanced with quality. Manufacturers in China often offer competitive pricing for bulk orders, making it an attractive option for cost-conscious buyers.
  • Lead Times and Availability: Ensure that the supplier can meet your required delivery schedules and has sufficient stock for your ongoing needs.
  • Documentation: Beyond the CoA, readily available Safety Data Sheets (SDS) and technical documentation are crucial for safe handling and proper usage.

The Advantage of Sourcing from China

China has become a global hub for chemical manufacturing, offering a wide array of compounds, including N-Tosyl-L-arginine, at competitive prices. For procurement managers, identifying reliable Chinese suppliers is key to optimizing budgets without sacrificing quality. Many Chinese chemical manufacturers have invested heavily in quality control systems and adhere to international standards, making them valuable partners for global research and industry. When inquiring, it is beneficial to clearly state your required quantity and purity specifications to receive accurate quotes.

How to Initiate a Purchase Inquiry

To buy N-Tosyl-L-arginine, start by identifying potential suppliers through online directories, chemical databases, or industry trade shows. Once you have a shortlist, send a detailed inquiry including the CAS number (1159-15-5), required quantity, desired purity, and any specific packaging or delivery requirements. Requesting pricing for different quantities, including bulk purchase options, will allow for effective budget planning. Building a good working relationship with a chosen supplier can ensure long-term supply stability and potentially better pricing on future orders.

In summary, N-Tosyl-L-arginine (CAS 1159-15-5) is a vital chemical intermediate and research reagent. By focusing on quality assurance, evaluating supplier credentials, and understanding market pricing, particularly from Chinese manufacturers, you can secure a reliable supply chain for your peptide synthesis and biochemical research needs.