For any pharmaceutical company, the quality and reliability of chemical intermediates are paramount. These compounds serve as the foundational building blocks for active pharmaceutical ingredients (APIs), directly impacting the efficacy, safety, and consistency of the final drug product. When sourcing critical intermediates such as 1,3-Dihydro-4-(2-hydroxyethyl)-2H-indole-2-one (CAS 139122-19-3), a structured approach is essential to ensure you partner with the right manufacturer or supplier.

Understanding the Intermediate: 1,3-Dihydro-4-(2-hydroxyethyl)-2H-indole-2-one

This specific intermediate, also known as 4-(2-hydroxyethyl)-1,3-dihydroindol-2-one, is a valuable component in organic synthesis, particularly within the pharmaceutical sector. Its molecular formula is C10H11NO2, with a molecular weight of 177.20 g/mol. It is characterized as a pale beige to brown solid, typically with a melting point around 148-150°C. Its significance is often highlighted in its role as a key intermediate for compounds like Ropinirole, used in treating Parkinson's disease. Ensuring high purity, often above 98%, is critical for its intended applications and to avoid unwanted side reactions or impurities in the final API.

Key Considerations When Sourcing Intermediates

When embarking on the process to buy or purchase pharmaceutical intermediates, several factors should guide your selection:

  • Purity and Quality Control: A reputable manufacturer will have stringent quality control measures in place. Look for suppliers who provide detailed Certificates of Analysis (CoA) and maintain consistent batch-to-batch quality. For intermediates like CAS 139122-19-3, verifying purity is non-negotiable.
  • Supply Chain Reliability: For commercial production, a stable and reliable supply chain is crucial. Consider the supplier's production capacity, lead times, and their ability to scale up to meet your projected volumes. A manufacturer based in regions with robust chemical production infrastructure, such as China, can often offer both quality and scale.
  • Regulatory Compliance: Ensure the supplier can provide necessary documentation, such as MSDS (Material Safety Data Sheets) and support for regulatory filings if required.
  • Pricing and Cost-Effectiveness: While quality is paramount, competitive pricing is also a significant factor. Direct sourcing from a manufacturer often yields better cost-effectiveness, allowing for better margins or more affordable end products.
  • Technical Support and Communication: A responsive and knowledgeable supplier can provide valuable technical support, answer queries promptly, and facilitate smooth transactions. Good communication is key when discussing bulk orders or specific technical requirements.

Choosing the Right Supplier in China

China has emerged as a global hub for chemical manufacturing, offering a vast array of intermediates and APIs. For 1,3-Dihydro-4-(2-hydroxyethyl)-2H-indole-2-one, partnering with an experienced Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. can provide significant advantages. We are committed to delivering high-quality products with a strong emphasis on purity and consistency, backed by competitive pricing and reliable logistics. Our dedication to serving the pharmaceutical industry means we understand the critical nature of timely and accurate supply, making us an ideal partner for your sourcing needs.

When you need to secure a consistent supply of critical intermediates, remember to prioritize these aspects. By doing so, you ensure the integrity of your research and the success of your pharmaceutical manufacturing operations. Contact us today to inquire about our offerings and discover how our expertise can support your procurement objectives.