For pharmaceutical manufacturers and R&D scientists focused on antifungal treatments, the efficient synthesis of ketoconazole is paramount. A cornerstone in this process is the intermediate, 2,4-Dichloroacetophenone, identified by its CAS number 2234-16-4. Understanding its properties and sourcing reliably is key to maintaining a robust supply chain.

What is 2,4-Dichloroacetophenone?

2,4-Dichloroacetophenone is an organic compound characterized by a phenyl ring substituted with two chlorine atoms and an acetophenone group. It typically appears as a colorless to light yellow crystalline solid. Its chemical structure makes it a valuable building block in various organic synthesis pathways, most notably in the pharmaceutical industry.

Its Critical Role in Ketoconazole Synthesis

The primary application driving the demand for 2,4-Dichloroacetophenone is its use as a key intermediate in the synthesis of ketoconazole. Ketoconazole is a broad-spectrum antifungal medication used to treat a variety of fungal infections. The precise chemical structure and purity of 2,4-Dichloroacetophenone directly influence the yield and quality of the final ketoconazole product. Therefore, sourcing from a reputable manufacturer that guarantees high purity (≥99.0%) is essential for any pharmaceutical production aiming for efficacy and compliance.

Beyond Pharmaceuticals: Agrochemical Applications

While its role in ketoconazole synthesis is significant, 2,4-Dichloroacetophenone also serves as an intermediate in the agrochemical sector. It is utilized in the production of certain pesticides and herbicides, contributing to crop protection and agricultural productivity. This dual utility underscores its importance as a versatile chemical intermediate.

Sourcing Strategies for Pharmaceutical Professionals

When looking to buy 2,4-Dichloroacetophenone, procurement managers and R&D scientists should prioritize suppliers who offer:

  • High Purity: Ensure the product meets stringent specifications for pharmaceutical or agrochemical applications.
  • Consistent Supply: Reliable manufacturers with strong production capabilities are crucial for uninterrupted operations.
  • Competitive Pricing: Sourcing from leading Chinese suppliers can offer significant cost advantages.
  • Technical Support: Access to technical data sheets, COAs, and responsive customer service is invaluable.

As a leading supplier in China, we understand the critical demands of the pharmaceutical and agrochemical industries. We are committed to providing high-quality 2,4-Dichloroacetophenone (CAS 2234-16-4) to support your research and manufacturing needs. Contact us today to inquire about price and availability, and to request a sample to ensure it meets your exact requirements.