For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount. L-Proline Benzyl Ester Hydrochloride (CAS 16652-71-4) stands out as a critical compound, primarily recognized for its role as an intermediate in the synthesis of Lisinopril. Understanding its properties and how to effectively source it can significantly streamline your development and manufacturing processes.

Understanding L-Proline Benzyl Ester Hydrochloride

L-Proline Benzyl Ester Hydrochloride is a derivative of the amino acid L-Proline. Its chemical structure makes it an invaluable building block, particularly in peptide synthesis and the creation of chiral pharmaceutical compounds. Key specifications to look for when purchasing include its appearance (typically a white to off-white powder) and its assay, with ≥98.0% purity being a common and desirable standard. Its melting point typically ranges from 148-151°C, providing an indication of its crystalline integrity.

The Importance of Purity and Quality

In pharmaceutical manufacturing, the purity of intermediates directly impacts the quality and efficacy of the final drug product. For Lisinopril synthesis, using a high-purity L-Proline Benzyl Ester Hydrochloride ensures fewer side reactions, better yields, and ultimately, a safer and more effective medication. As a manufacturer, we prioritize rigorous quality control measures to guarantee that every batch meets the specified purity levels. When you are looking to buy L-Proline Benzyl Ester Hydrochloride, always request a Certificate of Analysis (COA) to verify its specifications.

Applications Beyond Lisinopril Synthesis

While its primary commercial application is as a Lisinopril intermediate, L-Proline Benzyl Ester Hydrochloride's utility extends further. It is frequently employed in solid-phase peptide synthesis (SPPS) as a protected amino acid component. Its chiral nature also makes it a sought-after building block for asymmetric synthesis, enabling the creation of enantiomerically pure compounds, which are crucial for many modern pharmaceuticals. Researchers in academic institutions and biotech firms also utilize this compound in the development of novel amino acid derivatives and catalysts.

Navigating the Sourcing Process

When seeking to purchase L-Proline Benzyl Ester Hydrochloride, consider partnering with a reliable manufacturer or supplier. Key considerations include:

  • Manufacturer Reputation: Look for established manufacturers with a proven track record in producing high-purity intermediates.
  • Supply Chain Reliability: Ensure the supplier can consistently meet your volume requirements with timely deliveries. This is crucial for uninterrupted production schedules.
  • Technical Documentation: Access to comprehensive technical data, including COAs and Material Safety Data Sheets (MSDS), is essential for R&D and safety compliance.
  • Competitive Pricing: While quality is paramount, competitive pricing for bulk quantities can significantly impact your cost of goods. Obtain quotes from several reputable suppliers.

As a dedicated manufacturer of fine chemical intermediates, we are committed to providing L-Proline Benzyl Ester Hydrochloride that meets the highest industry standards. We understand the critical nature of pharmaceutical sourcing and strive to be your trusted supplier. If you are seeking to buy this essential intermediate or require a quotation for bulk supply, do not hesitate to contact us. Our team is ready to assist you with your specific needs and ensure a seamless procurement experience.