For researchers and procurement specialists in the life sciences and chemical industries, sourcing high-quality biochemicals is paramount to experimental success. L-Propargylglycine, a compound with CAS number 198774-27-5, is a key reagent widely sought after for its roles as a CSE inhibitor and in sophisticated peptide synthesis. Navigating the market to find reliable suppliers and understanding the purchasing process are critical steps.

L-Propargylglycine is characterized by its appearance as a white to off-white solid or powder, and its significant utility stems from its ability to inhibit cystathionine γ-lyase (CSE), an enzyme crucial for hydrogen sulfide production. Its application in research spans from studies on cardiovascular health and renal function to broader investigations into cellular signaling pathways. Furthermore, its incorporation into peptide synthesis allows for the creation of novel biomolecules with tailored properties, often leveraging its alkyne functionality for click chemistry reactions.

When looking to purchase L-Propargylglycine, several factors should be considered. Firstly, purity is a critical parameter. High-purity L-Propargylglycine is essential for reliable experimental outcomes, particularly in sensitive biochemical assays and precise peptide construction. Suppliers typically provide certificates of analysis (CoA) detailing purity levels, often determined by HPLC. Secondly, consistency in supply and batch-to-batch quality are vital for ongoing research projects.

The process of buying L-Propargylglycine usually involves identifying reputable chemical suppliers, requesting quotes, and verifying product specifications. Many suppliers offer various packaging sizes, from grams for laboratory use to larger quantities for bulk manufacturing or extensive research programs. When making an inquiry, it is often beneficial to specify the required quantity, purity level, and intended application to receive the most accurate pricing and availability information.

Choosing a supplier that offers robust technical support and clear documentation, such as Safety Data Sheets (SDS) and CoAs, is highly recommended. These resources provide essential information for safe handling, storage, and experimental integration of L-Propargylglycine. Whether you are investigating hydrogen sulfide signaling or synthesizing complex peptide structures, securing a dependable supply of L-Propargylglycine is a foundational step toward achieving your research objectives.