As a critical building block in organic synthesis, Methyl 5-Nitrosalicylate (CAS 17302-46-4) is sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors. Sourcing this compound efficiently and reliably requires a keen understanding of its properties, quality requirements, and the supplier landscape. This guide is designed for procurement managers and R&D scientists looking to secure a consistent supply of high-quality Methyl 5-Nitrosalicylate.

Understanding Methyl 5-Nitrosalicylate (also known as Methyl 2-hydroxy-5-nitrobenzoate) begins with its chemical identity. Its molecular formula, C8H7NO5, and CAS number, 17302-46-4, are key identifiers. The compound's structure features a hydroxyl group and a nitro group on a methyl ester of salicylic acid. This arrangement dictates its reactivity and utility as an intermediate in the synthesis of more complex molecules. Common applications include its use in developing new pharmaceutical agents, such as potential antimicrobial compounds and nonsteroidal anti-inflammatory drugs (NSAIDs), as well as in the creation of specialized agrochemicals like herbicides. The quality of this intermediate directly impacts the efficacy and yield of downstream products, making purity a paramount concern.

When sourcing Methyl 5-Nitrosalicylate, several quality parameters are crucial. Purity levels, typically specified as ≥98% (often by HPLC), are essential for predictable reaction outcomes. Manufacturers should provide detailed Certificates of Analysis (CoA) confirming purity, moisture content (e.g., ≤0.2%), and potentially other trace impurities. Physical appearance—often described as white to pale cream or orange crystalline powder—can also be an indicator of quality. For industrial-scale procurement, consistent batch-to-batch quality is non-negotiable. Working with reputable manufacturers who implement stringent quality control measures is therefore vital.

The global supply chain for fine chemicals like Methyl 5-Nitrosalicylate is diverse, with many reliable manufacturers and suppliers based in China. When selecting a supplier, consider factors beyond just the price. A responsive supplier who can provide technical support, flexible packaging options (e.g., 25 kg/drum), and clear communication regarding lead times and shipping is invaluable. It's advisable to request samples for internal testing before committing to large orders to ensure the material meets your specific application requirements. Furthermore, understanding the supplier's manufacturing capabilities and their adherence to international quality standards can provide added confidence.

Pricing for Methyl 5-Nitrosalicylate can vary based on purity, quantity, and market demand. For bulk purchases, buyers can often negotiate more favorable pricing. It is recommended to obtain multiple quotes from different suppliers to benchmark pricing and identify the most cost-effective option without compromising on quality. For smaller quantities needed for research and development, readily available stock from specialized chemical suppliers can ensure quick turnaround times.

In conclusion, securing a reliable supply of high-purity Methyl 5-Nitrosalicylate is a strategic decision for any company involved in advanced chemical synthesis. By focusing on quality parameters, carefully evaluating suppliers, and understanding market dynamics, procurement managers and scientists can ensure they obtain the essential intermediate needed for successful product development. For businesses seeking a trusted manufacturer and supplier of Methyl 5-Nitrosalicylate in China, reaching out for quotes and product samples is the first step towards a productive partnership.