For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is paramount to successful drug development. One such critical intermediate is N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine, identified by CAS number 162012-67-1. Understanding its properties, applications, and where to procure it from reliable manufacturers is key to ensuring a stable and efficient supply chain.

Understanding N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

This chemical compound is a quinazolinamine derivative, recognized for its role as a crucial building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its chemical structure and reactive groups make it particularly valuable in the creation of complex organic molecules. Typically supplied as a solid, its purity is a critical factor for its downstream applications. Manufacturers often guarantee a purity of 97% minimum, which is essential for pharmaceutical-grade intermediates.

Key Applications in Drug Synthesis

The primary application of N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine lies in its use as a pharmaceutical intermediate. It is notably employed in the synthesis of drugs designed to treat a range of serious conditions, including various types of cancer. Its structural features are vital for developing targeted therapies that inhibit specific cellular pathways implicated in disease progression. Furthermore, it finds utility in the synthesis of compounds aimed at treating diseases affecting the respiratory tract, lungs, and gastrointestinal tract. For R&D scientists, having a consistent and high-purity supply of this intermediate is fundamental to advancing their research and developing novel therapeutic agents.

Procurement from China Manufacturers

China has emerged as a significant global hub for the manufacturing of pharmaceutical intermediates. For companies looking to buy N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine, sourcing from reputable Chinese manufacturers offers several advantages, including competitive pricing and large-scale production capabilities. When selecting a supplier, it is crucial to verify their adherence to international quality standards, their production capacity, and their track record for reliable delivery. Companies specializing in fine chemicals and pharmaceutical intermediates often provide comprehensive product documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), which are vital for regulatory compliance and quality assurance. Engaging with a knowledgeable manufacturer or supplier can streamline the procurement process and ensure that you receive a product that meets your exact specifications.

Ensuring Supply Chain Stability

For procurement managers, establishing a stable supply chain for critical intermediates like CAS 162012-67-1 is a strategic imperative. This involves building strong relationships with trusted manufacturers, understanding their production capabilities, and forecasting demand accurately. By partnering with experienced suppliers who can offer consistent quality and timely delivery, companies can mitigate risks associated with supply chain disruptions and focus on their core business of drug innovation and production. Obtaining price quotes and samples from multiple manufacturers can also help in identifying the best value proposition.

In conclusion, N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is an indispensable intermediate for pharmaceutical research and production. By understanding its applications and leveraging the expertise of manufacturers and suppliers, particularly those in China, businesses can secure a reliable source for this vital chemical building block.