For professionals in the chemical and pharmaceutical industries, acquiring high-quality raw materials is foundational to product development and manufacturing success. N-Boc-L-Histidine (CAS 17791-52-5) is one such critical compound, widely used in peptide synthesis and as a pharmaceutical intermediate. This guide is designed to assist buyers in understanding what to look for when sourcing N-Boc-L-Histidine, from purity specifications to supplier reliability.

N-Boc-L-Histidine is an important amino acid derivative where the alpha-amino group of L-histidine is protected by a tert-butyloxycarbonyl (Boc) group. This protection is crucial for controlled peptide synthesis, preventing unwanted side reactions and ensuring the correct sequence of amino acids is built. The imidazole side chain of histidine also plays a key role in the biological activity of many peptides and proteins, making N-Boc-L-Histidine an indispensable component for researchers and manufacturers alike.

When you plan to buy N-Boc-L-Histidine, the first critical factor to consider is purity. For most applications, especially in pharmaceutical synthesis and sensitive biochemical research, a high purity level (typically ≥98% or ≥99% as determined by HPLC) is essential. Lower purity grades may contain impurities that can affect reaction yields, introduce unwanted side products, or compromise the efficacy of the final product. Therefore, always request a Certificate of Analysis (CoA) from your supplier to verify the purity and other key specifications.

The second major consideration is supplier reliability. Choosing a manufacturer or distributor that has a proven track record in the chemical industry is vital. Look for suppliers who offer consistent product quality, timely delivery, and responsive customer service. For bulk purchases, establishing a stable supply chain is paramount to avoid production delays. Many companies turn to manufacturers in China for N-Boc-L-Histidine due to the competitive pricing and extensive manufacturing capabilities available. However, it's crucial to vet these suppliers to ensure they meet international quality standards.

When evaluating N-Boc-L-Histidine prices, consider the quantity you need. Bulk purchases often come with significant discounts, making it more cost-effective for large-scale operations. Compare quotes from multiple reputable suppliers to find the best balance between price and quality. Don't hesitate to ask for samples if available, to test the material in your specific application before committing to a large order.

As a dedicated supplier of N-Boc-L-Histidine, we are committed to providing our clients with high-quality products and reliable service. We understand the demands of the pharmaceutical and research sectors and strive to be a trusted partner for all your amino acid derivative needs. We encourage you to contact us for a quote on N-Boc-L-Histidine and to discuss how we can support your supply chain requirements with competitive pricing and unwavering quality.