For procurement managers and R&D scientists in the pharmaceutical sector, securing high-quality raw materials is paramount. N-Cbz-L-Phenylglycine, a vital amino acid derivative and chiral building block, plays a significant role in the synthesis of numerous active pharmaceutical ingredients (APIs) and complex therapeutic molecules. Understanding its properties and how to source it effectively can streamline your supply chain and ensure project success.

What is N-Cbz-L-Phenylglycine?

N-Cbz-L-Phenylglycine, identified by CAS number 53990-33-3, is a protected form of the non-proteinogenic amino acid L-phenylglycine. The Cbz (carbobenzyloxy) group serves as a protecting group for the amine functionality, allowing for selective reactions elsewhere in the molecule during multi-step synthesis. Its chiral nature makes it particularly useful in stereoselective synthesis, a cornerstone of modern drug development.

Key Applications in the Pharmaceutical Industry

The versatility of N-Cbz-L-Phenylglycine makes it a sought-after intermediate for a variety of applications:

  • API Synthesis: It is a crucial precursor for the synthesis of several important APIs, contributing to the development of life-saving medications. As a potential manufacturer, we focus on delivering consistent purity to meet these demanding requirements.
  • Peptide Synthesis: As a protected amino acid, it is employed in solid-phase and solution-phase peptide synthesis, enabling the creation of therapeutic peptides and peptidomimetics. If you are looking to buy these specialized building blocks, consider reliable suppliers.
  • Chiral Pool Synthesis: Its defined stereochemistry allows it to be used as a chiral starting material, guiding the stereochemical outcome of complex synthetic routes. Sourcing high-enantiomeric-purity material is critical here.
  • Medicinal Chemistry Research: Researchers utilize N-Cbz-L-Phenylglycine in the exploration of new molecular entities, drug discovery, and structure-activity relationship (SAR) studies. When researching 'N-Cbz-L-Phenylglycine price', compare suppliers carefully.

Sourcing Strategies for Procurement Professionals

When looking to purchase N-Cbz-L-Phenylglycine, several factors are crucial:

  • Purity and Enantiomeric Excess: Ensure the supplier provides detailed certificates of analysis (CoA) specifying purity and enantiomeric excess (ee). For pharmaceutical applications, a purity of 99% or higher is often required.
  • Manufacturer Reliability: Partnering with a reputable manufacturer in China or a trusted global distributor minimizes supply chain risks. Look for suppliers with a proven track record and robust quality control processes.
  • Lead Times and Packaging: Confirm availability, lead times, and suitable packaging options to meet your production or research timelines.
  • Regulatory Compliance: Verify that the product and its manufacturing processes comply with relevant industry standards and regulations.

As NINGBO INNO PHARMCHEM CO.,LTD., we understand the critical importance of quality and reliability. We are a dedicated N-Cbz-L-Phenylglycine supplier committed to providing the pharmaceutical industry with high-grade intermediates. Contact us today to request a quote or inquire about sample availability and secure your supply of this essential compound.