For procurement professionals and R&D scientists in the chemical and pharmaceutical industries, sourcing critical compounds like Nicotinamide N-oxide (CAS 1986-81-8) requires a strategic approach. As a key intermediate and research chemical, its availability from dependable manufacturers and suppliers is crucial for ongoing projects. This guide outlines what buyers should consider when looking to buy Nicotinamide N-oxide.

Nicotinamide N-oxide, with its distinct chemical identity (C6H6N2O2, CAS 1986-81-8), serves multiple important functions. It is recognized as an in vivo metabolite of nicotinamide, contributing to our understanding of Vitamin B3 metabolism. Furthermore, its potent antagonistic activity against the CXCR2 receptor makes it invaluable in immunology and inflammation research, paving the way for potential therapeutic developments. When sourcing this compound, understanding these applications helps in defining the required purity and specifications.

As a manufacturer, particularly one based in China, offering Nicotinamide N-oxide means adhering to strict quality control measures. Buyers should look for clear documentation regarding purity levels, typically stated as 97% or higher. Certificates of Analysis (CoA) are essential, detailing physical properties such as melting point (around 291-293 °C with decomposition) and appearance (usually a white powder). A reliable supplier will readily provide this information.

When evaluating potential suppliers, consider factors beyond just the price. A comprehensive inquiry should include questions about production capacity, lead times for delivery, and any available technical support. For bulk purchases, negotiating a favorable price is a key objective. Working directly with a chemical manufacturer often yields better cost efficiencies compared to multi-tiered distribution channels. Requesting a quote from multiple verified suppliers is a standard practice to ensure competitive market rates.

The global demand for specialized chemicals like Nicotinamide N-oxide necessitates a robust supply chain. Companies that offer international shipping and possess experience in handling chemical exports are preferred. Whether you are looking to purchase small quantities for laboratory research or larger volumes for pilot-scale synthesis, identifying a trustworthy partner is paramount. By focusing on quality, reliability, and competitive pricing, procurement managers can successfully secure their supply of Nicotinamide N-oxide.