For R&D scientists and procurement managers in the pharmaceutical sector, sourcing critical raw materials is a cornerstone of successful drug development. One such vital compound is cis-5-Norbornene-exo-2,3-dicarboxylic anhydride, particularly known for its role as a Lurasidone intermediate. Understanding where to buy and what to look for in a supplier can significantly impact project timelines and outcomes.

Understanding cis-5-Norbornene-exo-2,3-dicarboxylic anhydride (CAS 2746-19-2)

This bicyclic anhydride, identified by CAS number 2746-19-2, presents as a white solid with a purity typically exceeding 98.0%. Its unique structural features make it an indispensable building block in complex organic synthesis, most notably in the production pathway for Lurasidone, an important antipsychotic medication. The demand for high-purity intermediates like this underscores the need for dependable manufacturing partners.

Key Considerations for Pharmaceutical Procurement

When sourcing pharmaceutical intermediates, several factors are paramount:

  • Purity and Specifications: As indicated by its specifications, consistently high purity (≥98.0%) is crucial. Any deviation can impact downstream reactions and the quality of the final Active Pharmaceutical Ingredient (API). Ensure the supplier provides a Certificate of Analysis (CoA) detailing purity and impurity profiles.
  • Supplier Reliability: Partnering with an experienced manufacturer, especially one based in China known for its chemical production capabilities, can offer significant advantages. A reliable supplier guarantees consistent batch quality and stable supply, crucial for uninterrupted production cycles.
  • Regulatory Compliance: Understanding patent landscapes and ensuring compliance with relevant chemical regulations is vital. Reputable suppliers will be transparent about patent status and regulatory adherence.
  • Technical Support: Access to technical data, synthesis information, and responsive customer service can streamline the procurement and application process.

Finding Your Ideal Supplier in China

For procurement managers seeking to buy cis-5-Norbornene-exo-2,3-dicarboxylic anhydride, focusing on manufacturers with proven track records in producing pharmaceutical intermediates is key. Look for suppliers who can offer:

  • Competitive Pricing: Obtaining quotes from multiple manufacturers will help identify cost-effective solutions without compromising on quality.
  • Scalability: The ability to scale up production from laboratory quantities to commercial volumes is essential for projects progressing through clinical trials and into market launch.
  • Logistics and Delivery: Efficient shipping and logistics are critical. A supplier with experience in international shipping can ensure timely delivery, whether by air or sea freight.

By carefully evaluating potential manufacturers and suppliers, pharmaceutical companies can secure a high-quality, consistently available source of cis-5-Norbornene-exo-2,3-dicarboxylic anhydride, thereby supporting the efficient and cost-effective production of essential medications. Engaging with trusted chemical manufacturers in China offers a strategic advantage in securing this vital intermediate.