For procurement managers and R&D scientists in the pharmaceutical sector, sourcing high-quality intermediates is paramount for successful drug development and manufacturing. One such critical compound is 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine, identified by CAS number 161599-46-8. This article serves as a guide for buyers looking to procure this essential pharmaceutical intermediate, focusing on what to look for when selecting a manufacturer and supplier.

Understanding the Importance of CAS 161599-46-8
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine is a vital intermediate, particularly in the synthesis of anticancer drugs like capecitabine. Its specific chemical structure, C13H16FN3O6, and purity levels significantly impact the efficacy and safety of the final active pharmaceutical ingredient (API). As a buyer, ensuring you receive a product that meets stringent specifications is non-negotiable. Therefore, identifying a reliable manufacturer and supplier is the first step towards a successful procurement.

Key Considerations When Sourcing from China
When looking to buy pharmaceutical intermediates like CAS 161599-46-8 from China, consider the following:

  • Manufacturer Reputation and Certifications: Seek out manufacturers with a proven track record and relevant certifications (e.g., ISO, GMP compliance). A reputable supplier will readily provide documentation supporting their quality control processes.
  • Purity and Assay Specifications: Verify that the product meets the required purity levels (often >99% for pharmaceutical intermediates). Request Certificates of Analysis (CoA) to confirm the specifications.
  • Supply Chain Stability: Ensure the manufacturer or supplier has a stable production capacity and a reliable logistics network to guarantee timely delivery. A consistent supply is crucial for uninterrupted manufacturing.
  • Technical Support and Communication: Look for a supplier who offers excellent technical support and clear communication. Being able to discuss product details, specifications, and potential custom requirements is vital.
  • Pricing and Payment Terms: While quality is paramount, competitive pricing is also a key factor. Understand the payment terms and inquire about bulk purchase discounts from your chosen supplier.

Navigating the Procurement Process
To procure 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine, initiate contact with potential suppliers. Clearly state your requirements, including quantity, desired purity, packaging specifications, and delivery timeline. Requesting a quotation early in the process is recommended. Many manufacturers in China are equipped to handle international orders and provide necessary export documentation. Leveraging online platforms and industry directories can help identify potential partners, but thorough due diligence is essential.

Partnering for Success
As your dedicated pharmaceutical intermediate manufacturer and supplier, we understand the critical nature of your supply chain. We are committed to providing high-purity 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine (CAS 161599-46-8) with reliable quality and timely delivery. Our expertise in chemical synthesis and commitment to customer satisfaction make us an ideal partner for your pharmaceutical development needs. Contact us today to get a quote and discuss your specific requirements for this vital intermediate.