Sourcing Pharmaceutical Intermediates: A Guide to 2-Hydroxy-5-methyl-3-nitropyridine
The pharmaceutical industry's success hinges on the consistent availability of high-quality building blocks and intermediates. Among these, heterocyclic compounds like 2-Hydroxy-5-methyl-3-nitropyridine (CAS: 7464-14-4) play a pivotal role in the synthesis of Active Pharmaceutical Ingredients (APIs). For procurement professionals and medicinal chemists, understanding the sourcing and chemical characteristics of such intermediates is crucial for efficient drug development.
2-Hydroxy-5-methyl-3-nitropyridine is valued for its unique structural features: a pyridine core functionalized with a hydroxyl group, a methyl group, and a nitro group. This combination makes it a versatile starting material for creating complex drug molecules. The hydroxyl group can participate in various derivatization reactions, such as esterification or etherification, while the nitro group can be reduced to an amine, opening pathways for further functionalization, including amide formation or diazotization. These chemical attributes are highly sought after in medicinal chemistry for exploring new therapeutic agents.
When seeking to purchase 2-Hydroxy-5-methyl-3-nitropyridine, discerning buyers look for reliability and purity. A reputable manufacturer or supplier will typically provide detailed specifications, including assay results (often ≥98.0%), and ensure consistent batch-to-batch quality. For organizations looking for such specialized chemicals, identifying a reliable manufacturer in China can offer significant advantages in terms of both cost and supply chain efficiency. The ability to obtain a quotation based on specific quantity requirements is a standard part of the procurement process for these materials.
The effective utilization of this compound in pharmaceutical synthesis requires a thorough understanding of its reactivity and stability. Its role as a key intermediate means that its quality directly impacts the yield and purity of downstream products. Researchers often search for specific CAS numbers like 7464-14-4 to pinpoint trustworthy sources. The broader applications of this compound extend into other areas of fine chemical synthesis, highlighting its importance as a general chemical building block.
For those in the pharmaceutical sector, the strategic sourcing of intermediates like 2-Hydroxy-5-methyl-3-nitropyridine is a critical business decision. Partnering with a supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to not only the chemical itself but also the expertise and reliability needed to support ongoing research and manufacturing operations. The search for cost-effective yet high-quality pharmaceutical intermediates is an ongoing challenge, and a dependable supplier can be a significant asset.
Perspectives & Insights
Core Pioneer 24
“The ability to obtain a quotation based on specific quantity requirements is a standard part of the procurement process for these materials.”
Silicon Explorer X
“The effective utilization of this compound in pharmaceutical synthesis requires a thorough understanding of its reactivity and stability.”
Quantum Catalyst AI
“Its role as a key intermediate means that its quality directly impacts the yield and purity of downstream products.”