The pharmaceutical industry relies heavily on a diverse range of chemical intermediates to synthesize life-saving drugs and innovative therapies. Among these, amino acid derivatives play a pivotal role, forming the backbone of peptides and complex organic molecules. This article focuses on Nalpha-Fmoc-L-lysine hydrochloride (CAS 139262-23-0), a key pharmaceutical intermediate, and discusses its applications and the importance of sourcing it from reputable manufacturers, particularly within China's robust chemical supply chain.

Nalpha-Fmoc-L-lysine hydrochloride is a protected form of the amino acid lysine. Lysine is an essential amino acid characterized by its epsilon-amino group, which requires protection during various synthetic processes to prevent unwanted reactions. The Nalpha-Fmoc group serves as a temporary protecting group for the alpha-amino nitrogen, commonly employed in solid-phase peptide synthesis (SPPS). The hydrochloride salt form enhances its handling and stability.

Key Applications in Pharmaceuticals:

The primary application of Nalpha-Fmoc-L-lysine hydrochloride lies in the synthesis of peptides. This intermediate is indispensable for researchers and manufacturers involved in:

  • Peptide Drug Manufacturing: Many modern pharmaceuticals are peptide-based, targeting conditions ranging from diabetes and obesity to cancer and autoimmune diseases. Lysine derivatives are frequently incorporated into these peptide chains to modify their properties, such as solubility, half-life, and receptor binding.
  • Drug Delivery Systems: The unique structure of lysine, with its reactive side chain, makes it an excellent candidate for conjugation. Nalpha-Fmoc-L-lysine hydrochloride can be used to create modified peptides for targeted drug delivery or to develop advanced drug carriers, such as specialized nanoparticles, as seen in some photodynamic therapy research.
  • Biochemical Reagents: Beyond direct drug synthesis, this compound serves as a valuable reagent in biochemical research, aiding in the study of protein-protein interactions, enzyme mechanisms, and the development of diagnostic tools.

Sourcing from China: A Strategic Advantage:

China has emerged as a global hub for chemical manufacturing, offering high-quality pharmaceutical intermediates at competitive prices. For companies looking to buy Nalpha-Fmoc-L-lysine hydrochloride, partnering with a Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. provides several advantages, including a stable supply chain, rigorous quality control, and the ability to scale production according to demand. We understand the critical nature of these intermediates and ensure our products meet international standards for purity and consistency.

When procuring this intermediate, it is essential to partner with a supplier that provides detailed product specifications, including CAS number (139262-23-0), molecular formula (C21H25ClN2O4), and purity levels (typically assayed by HPLC). We invite procurement managers and R&D scientists to contact us to discuss your requirements for Nalpha-Fmoc-L-lysine hydrochloride, whether for research purposes, pilot-scale production, or large-scale manufacturing. Secure your supply of this vital pharmaceutical intermediate today.