In the competitive landscape of pharmaceutical manufacturing, securing a reliable supply of high-quality intermediates is paramount. For companies involved in the production of statins, particularly Pitavastatin, understanding the nuances of sourcing key building blocks like Tert-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate (CAS 147489-06-3) is crucial. This article aims to guide procurement managers and R&D scientists in making informed decisions.

Pitavastatin, a well-known HMG-CoA reductase inhibitor, is widely used to manage hypercholesterolemia. Its synthesis involves several complex steps, with specific chiral intermediates playing a pivotal role in achieving the desired stereochemistry and efficacy of the final Active Pharmaceutical Ingredient (API). Tert-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is one such critical intermediate, prized for its intricate structure and high purity.

When searching for this essential compound, B2B buyers often look for specific attributes. The CAS number 147489-06-3 serves as a unique identifier, and buyers will commonly search using terms like 'pitavastatin intermediate manufacturer' or 'buy CAS 147489-06-3'. The demand for 'high purity pitavastatin intermediate for sale' is consistently high, as even minor impurities can impact the final drug product's safety and effectiveness. Procurement professionals will also be keenly interested in the 'pharmaceutical intermediates price' and seek out reliable 'CAS 147489-06-3 suppliers in China' to leverage cost advantages.

Partnering with a reputable manufacturer and supplier from China offers significant benefits. These include access to advanced manufacturing capabilities, stringent quality control processes, and often, more competitive pricing structures. For instance, a dedicated manufacturer can ensure a stable supply chain, mitigating risks associated with fluctuating market demands or production disruptions. When seeking to purchase this intermediate, inquire about their production capacity, quality assurance certifications (such as ISO), and lead times. A good supplier will provide detailed Certificates of Analysis (CoA) with each batch, confirming purity and specifications.

To effectively procure Tert-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate, consider the following tips:

  • Verify Purity: Always request and review the CoA. Look for assay values typically at or above 99%.
  • Assess Supply Chain Stability: Understand the manufacturer's production capacity and inventory management.
  • Compare Pricing: Obtain quotes from multiple suppliers in China to ensure competitive pricing. Negotiate bulk purchase discounts.
  • Request Samples: Before committing to large orders, request samples for internal quality assessment and R&D validation.
  • Build Relationships: Establish strong relationships with trusted partners who can consistently deliver quality and support your long-term manufacturing goals.

By focusing on these key areas, pharmaceutical companies can ensure they are acquiring the highest quality Pitavastatin intermediates, thereby contributing to the successful development and production of vital medications. For those seeking a reliable source, exploring options from leading Chinese manufacturers is a strategic step towards optimizing your procurement process.