For pharmaceutical manufacturers and procurement specialists, securing a stable and high-quality supply of active pharmaceutical ingredient (API) intermediates is paramount. Among these critical compounds, 2-Chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone (CAS: 178688-43-2) stands out as a vital building block, particularly in the synthesis of Prasugrel Hydrochloride. This article aims to guide buyers in understanding the importance of this intermediate and how to effectively source it from reputable manufacturers and suppliers, especially focusing on the capabilities within China.

Understanding the Significance of 2-Chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Prasugrel Hydrochloride is a potent antiplatelet medication used to prevent blood clots in patients with acute coronary syndrome undergoing percutaneous coronary intervention. The efficacy and safety of the final drug product are directly linked to the quality of its constituent intermediates. 2-Chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone, with its specific chemical structure and high purity requirements, plays an indispensable role in the multi-step synthesis of Prasugrel Hydrochloride. Buyers often search for terms like 'buy 2-chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone' or '178688-43-2 supplier' when initiating their procurement process.

Key Specifications and Quality Considerations

When sourcing this intermediate, it is crucial to pay close attention to its specifications. A white to off-white crystalline powder with a purity of ≥99% is typically desired. Other important parameters include moisture content and impurity profiles, which must meet stringent pharmaceutical standards. Manufacturers who can provide detailed Certificates of Analysis (CoA) and support regulatory documentation are highly valued. Understanding these specifications helps in selecting the right manufacturer and ensuring product quality, which directly impacts the yield and purity of the final API.

Strategic Sourcing from China: A Competitive Advantage

China has emerged as a global powerhouse for chemical manufacturing, offering a vast array of pharmaceutical intermediates at competitive prices. For buyers looking to source 2-Chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone, partnering with a reliable Chinese manufacturer or supplier can offer significant advantages. These include cost-effectiveness, scalability, and access to a wide range of chemical expertise. When inquiring about 'prasugrel hydrochloride intermediate price' or looking for 'pharmaceutical intermediate sourcing China,' it’s essential to vet potential suppliers for their manufacturing capabilities, quality control systems, and adherence to international standards. Establishing a strong relationship with a trusted manufacturer is key to ensuring a consistent and reliable supply chain.

Navigating the Procurement Process

The procurement of pharmaceutical intermediates involves more than just price comparison. It requires a thorough evaluation of the supplier's reliability, technical support, and regulatory compliance. Buyers should be prepared to request detailed product information, inquire about sample availability for R&D purposes, and discuss lead times for bulk orders. For those seeking to purchase 2-chloro-1-cyclopropyl-2-(2-fluorophenyl)ethanone, engaging with experienced chemical suppliers who specialize in pharmaceutical intermediates is a strategic move. This ensures not only the quality of the product but also smooth transaction processes and timely delivery, ultimately supporting the successful manufacturing of life-saving medications.